Results 51 to 60 of about 339,095 (200)

The ongoing oleoylethanolamide story: Therapeutic implications in the control of obesity and its comorbidities

British Journal of Pharmacology, EarlyView.
The global burden of obesity continues to rise, demanding effective pharmacological strategies for individuals in whom prevention alone is insufficient. Recent incretin‐based and multi‐agonist therapies have delivered unprecedented weight loss, demonstrating that the simultaneous modulation of multiple metabolic pathways can optimize body weight ...
Marzia Friuli, Alessia Campagna, Barbara Eramo, Christian Sepe, Annarita Zuena, Silvana Gaetani, Adele Romano   +6 more
wiley   +1 more source

Expression of Exocytosis Proteins in Rat Supraoptic Nucleus Neurones [PDF]

Journal of Neuroendocrinology, 2012
In magnocellular neurones of the supraoptic nucleus (SON), the neuropeptides vasopressin and oxytocin are synthesised and packaged into large dense‐cored vesicles (LDCVs). These vesicles undergo regulated exocytosis from nerve terminals in the posterior pituitary gland and from somata/dendrites in the SON. Regulated exocytosis of LDCVs is considered to
Tobin, Vicky, Schwab, Yannick, Lelos, Nicholas, Onaka, Tatsushi, Pittman, Quentin, Ludwig, Mike   +5 more
openaire   +2 more sources

Alpha-synuclein expression in oxytocin neurons of young and old bovine brains

The Journal of Reproduction and Development
Understanding of central nervous system mechanisms underlying age-related infertility remains limited. Fibril α-synuclein, distinct from its monomeric form, is implicated in age-related diseases. Notably, fibril α-synuclein spreads among neurons,
Yvan Bienvenu NIYONZIMA, Yuuki ASATO, Hiroya KADOKAWA   +2 more
doaj   +1 more source

DISTRIBUTION OF OXYTOCIN AND VASOPRESSIN IN THE RAT SUPRAOPTIC AND PARAVENTRICULAR NUCLEUS [PDF]

Journal of Endocrinology, 1975
Abstract Netherlands Central Institute for Brain Research, Ijdijk 28, Amsterdam-0, The Netherlands (Received 3 July 1975) The 'classical' view on the distribution of oxytocin and vasopressin producing cells suggests that the paraventricular nucleus (PVN) is predominantly or entirely responsible for ...
Swaab, D.F., Nijvelt, F., Pool, C.W.
openaire   +3 more sources

Effects of noise stress on expression of Fos protein in rat brain

浙江大学学报. 农业与生命科学版, 2007
In the model of rats with noise stress, the expression of Fos protein in brain was examined by immunohistochemical method during the chronic stress process.
HU Jun-xiang, JIANG Yu-xin, YANG Qiong-xia, WANG Yan-qin, HUANG Pei-long   +4 more
doaj   +1 more source

Voluntary exercise mitigates the effects of peri‐adolescent social isolation on emotion recognition and the oxytocinergic system in male mice

Journal of Neuroendocrinology, Volume 38, Issue 11, November 2026.
Abstract Social isolation, particularly during adolescence, is known to affect cognitive, emotional, and social behaviors as well as brain modulatory systems such as the hypothalamic oxytocinergic system. Interestingly, recent evidence indicates that exercise can exert beneficial effects on behaviors through the activation of the oxytocinergic system ...
E. Van Loveren, S. Alfos, S. F. Guu, C. Ducroix‐Crepy, S. Hernández‐Ramírez, G. Ferreira, P. Lafenetre   +6 more
wiley   +1 more source

Glutamate Microstimulation of Local Inhibitory Circuits in the Supraoptic Nucleus From Rat Hypothalamus Slices

, 1997
Wuarin, Jean-Pierre. Glutamate microstimulation of local inhibitory circuits in the supraoptic nucleus from rat hypothalamus slices. J. Neurophysiol. 78: 3180–3186, 1997.
Jean-Pierre Wuarin
core   +1 more source

Na1.7: Stress-Induced Changes in Immunoreactivity within Magnocellular Neurosecretory Neurons of the Supraoptic Nucleus

Molecular Pain, 2013
Background Na v 1.7 is preferentially expressed, at relatively high levels, in peripheral neurons, and is often referred to as a “peripheral” sodium channel, and Na v 1.7-specific blockers are under study as potential pain therapeutics which might be ...
Joel A Black, Janneke GJ Hoeijmakers, Catharina G Faber, Ingemar SJ Merkies, Stephen G Waxman   +4 more
doaj   +1 more source

Cell populations and vasculature of supraoptic nucleus at the somatic zone.

, 2019
(A, A') Parenchymal glial cells are distinguished as two groups: cells having smooth rounded nuclei and vesicles similar to lipid droplets (asterisk) (A) and cells with polylobed nuclei containing lipid droplets or endosomes in the cytoplasm (asterisk ...
Ahmad Yamin bin Abdul Rahman (6852635), Michael P. Greenwood (613189), Kar-Wai Hong (3268704), Yea-Ling Tay (6852632), Fatma Zohra Djazouli Alim (6852629), Mark Rogers (2300428), Andre Souza Mecawi (6852638), Colin Campbell (527529), Bruce R. Southey (19329), Jonathan V. Sweedler (19333), Elena V. Romanova (240052), Charles C. T. Hindmarch (6852644), David Murphy (483511), Nicole Mahy (560969), Kok-Gan Chan (531824), Mohammad Rais Mustafa (6852641), José Antunes-Rodrigues (806125)   +16 more
core   +1 more source

Neurosteroid regulation of oxytocin and vasopressin release from the rat supraoptic nucleus

, 2003
In adult rats somato-dendritic release of oxytocin and vasopressin from magnocellular neurones in the supraoptic nucleus of the hypothalamus has important autoregulatory actions on the neuronal electrical activity, and in neonatal rats it plays a role in
Widmer, Hélène, Ludwig, Mike, Leng, Gareth, Bancel, Frédéric, Dayanithi, Govindan   +4 more
core   +2 more sources