Results 131 to 140 of about 1,582,405 (310)
, 2011 Network theory provides various tools for investigating the structural or functional topology of many complex systems found in nature, technology and society.
A. Arenas +54 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Relaciones Internacionales, 2016 El acaparamiento de tierras (land grabbing) refiere al proceso de adquisiciones a gran escala de tierras agrícolas en otros estados, desatado en el contexto de la convergencia de crisis internacionales —alimentaria, energética, financiera y climática— de
Sol Yamila MORA
doaj
Género; Colonialidad; Política pública; Salud; Sur global
, 2022 RESUMEN: Se propone un análisis de políticas públicas que articulan género y salud en América Latina, para repensar la dimensión global de la construcción de conceptos, indicadores e instrumentos de evaluación de impactos de estas políticas en la región.
López, Laura Cecilia +2 more
openaire +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Los estudios comparativos en el campo de la investigación urbana*
Estudios Demográficos y UrbanosEste trabajo examina el papel del método comparativo en la investigación urbana, prestando atención a su utilidad en la generación de teoría, y a las particularidades de las comparaciones entre ciudades de distintas regiones.
Martha Schteingart, Andrés Sierra
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
De CINVA a Siyabuswa: el trayecto errático de la vivienda de autoayuda global
ARQEn un proyecto piloto para la futura capital Bantustán en Siyabuswa, el estado sudafricano de la era del apartheid financió la investigación y construcción de 59 viviendas básicas entre 1977 y 1978, antes de frenar el esquema completo.
Hannah le Roux
doaj
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source