Results 91 to 100 of about 4,143,872 (340)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Simple structures axiomatized by almost sure theories
, 2015 In this article we give a classification of the binary, simple, $\omega$-categorical structures with SU-rank 1 and trivial pregeometry. This is done both by showing that they satisfy certain extension properties, but also by noting that they may be ...
Ahlman, Ove
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
İlahiyat Akademi, 2019 Oryantalistlerin nazarında Kur’an-ı Kerim’in mevcut mushaf tertibi, O’nun kompozisyon bütünlüğünden yoksun olmasına ve anlaşılmamasına neden olan başat unsurdur.
Hüseyin Polat
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Cumhuriyet Üniversitesi İlahiyat Fakültesi Dergisi, 2012 Bu yazıda aktif olarak işlenen bir tefsir dersi tecrübesi aktarılmaktadır. 2012-2013 öğretim yılında ilahiyat Fakültesi III. sınıfta yapılan derste, öğrencilere daha fazla rol verilerek azami fayda sağlanmak hedeflenmiştir.
İSMAİL ÇALIŞKAN
doaj
Science China Information Sciences, 2018 Although the mean square stabilization of hybrid systems by feedback control based on discretetime observations of state and mode has been studied by several authors since 2013, the corresponding almost sure stabilization problem has received little ...
G. Song, Zhenyu Lu, Bochao Zheng, X. Mao
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Reliable, resilient and sustainable water management: the Safe & SuRe approach
Global Challenges, 2016 Global threats such as climate change, population growth, and rapid urbanization pose a huge future challenge to water management, and, to ensure the ongoing reliability, resilience and sustainability of service provision, a paradigm shift is required ...
D. Butler +6 more
semanticscholar +1 more source