Results 81 to 90 of about 4,143,872 (340)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Improving Quality of Care in Primary Health-Care Facilities in Rural Nigeria
Background: Nigeria has a high population density but a weak health-care system. To improve the quality of care, 3 organizations carried out a quality improvement pilot intervention at the primary health-care level in selected rural areas.
Okoli Ugo +5 more
doaj +1 more source
Maximum Power Point Tracking of Photovoltaic System for Traffic Light Application
Photovoltaic traffic light system is a significant application of renewable energy source. The development of the system is an alternative effort of local authority to reduce expenditure for paying fees to power supplier which the power comes from ...
Riza Muhida +4 more
doaj +1 more source
Blacon Sure Start parent satisfaction survey [PDF]
This report evaluates Sure Start in Blacon during 2003.Commissioned and funded by Blacon Sure ...
Barrow, Marjorie +2 more
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sure Start Children's Centres: statutory guidance [PDF]
"References in this document to ‘the Childcare Act’ mean the Childcare Act 2006, as amended by the Apprenticeships, Skills, Children and Learning Act 2009 (the ASCL Act) unless specified otherwise. This guidance is made under the Childcare Act.
core
An almost sure energy inequality for Markov solutions to the 3D Navier-Stokes equations
We prove existence of weak martingale solutions satisfying an almost sure version of the energy inequality and which constitute a (almost sure) Markov process.Comment: Submitted for the proceedings of the conference "Stochastic partial differential ...
Romito, Marco
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Background Phase 1 drug trials are popular treatment options for patients with advanced disease, despite the greater levels of uncertainty associated with them. However, their meaning and consequences for patient-participants remains under-explored. This
Kate Escritt +3 more
doaj +1 more source
SURE: A method for decision-making under uncertainty
Managerial decision-making often involves the consideration of multiple criteria with high levels of uncertainty. Multi-attribute utility theory, a primary method proposed for decision-making under uncertainty, has been repeatedly shown to be difficult ...
R. Hodgett, S. Siraj
semanticscholar +1 more source

