Results 41 to 50 of about 3,094 (268)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Evaluating potential man-induced changes in fish communities at estuarine and surf-zone areas: a long-term case study in Southern Brasil

open access: yesFrontiers in Marine Science, 2015
Anthropogenic impacts as environmental degradation and fisheries have been historically associated with changes in structure and dynamics of fish assemblages.
Joao Vieira
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Surf Zone Turbulence and Suspended Sediment Dynamics—A Review

open access: yesJournal of Marine Science and Engineering, 2021
The existence of sandy beaches relies on the onshore transport of sand by waves during post-storm conditions. Most operational sediment transport models employ wave-averaged terms, and/or the instantaneous cross-shore velocity signal, but the models ...
Troels Aagaard   +4 more
doaj   +1 more source

CURRENTS IN THE SURF ZONE

open access: yesCoastal Engineering Proceedings, 1951
Surface and bottom currents in the surf zone were measured at 15 equally spaced points along two straight beaches with approximately parallel bottom contours. The measurements showed that offshore currents predominate over onshore currents at the bottom, while at the surface there is a slight predominance in the onshore direction.
D. L. Inman, W. H. Quinn
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The Role of Infragravity Waves in Near-Bed Cross-Shore Sediment Flux in the Breaker Zone

open access: yesJournal of Marine Science and Engineering, 2014
Results from a series of field experiments, conducted to investigate the influence of infragravity waves (from wave groups), ripple type and location relative to the breaker line on cross-shore suspended sediment flux close to the sea bed in nearshore ...
Samantha Kularatne   +1 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Wave-Induced Distribution of Microplastic in the Surf Zone

open access: yesFrontiers in Marine Science, 2020
In this study, the wave-induced distribution of 13 microplastic (MP) samples of different size, shape, and density was investigated in a wave flume with a sandy mobile beach bed profile.
Nils B. Kerpen   +5 more
doaj   +1 more source

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