Results 101 to 110 of about 1,645,777 (287)
Forces Acting on Sessile Droplet on Inclined Surfaces
Although many analytical, experimental and numerical studies have focused on droplet motion, the mechanics of the droplet while still in its static state, and just before motion starts, are not well understood. A study of static droplets would shed light on the threshold voltage (or critical inclination) for initiating electrically (or gravitationally)
Annapragada, S. Ravi +2 more
openaire +3 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Anisotropic particles near surfaces: Self-propulsion and friction
We theoretically study the phenomenon of self-propulsion through Casimir forces in thermal non-equilibrium. Using fluctuational electrodynamics, we derive a formula for the self-propulsion force for an arbitrary small object in two scenarios, i) for the ...
Krüger, Matthias, Müller, Boris
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Building on the social identity theory, this conceptual article proposes a process model to understand the linkage between workplace humor and the social identity change experiences of employees.
Sana Mumtaz
doaj +1 more source
Emotional Works and Turnover Intention of Sri Lankan Nurses
In the quest for the concept of emotional work, it is apparent that comparing to the international context there are much less research done in Sri Lanka.
M.K. Dinithi Padmasiri, A.M.T. Lakmali
doaj +1 more source
Center Vortex Model for the Infrared Sector of SU(3) Yang-Mills Theory - Vortex Free Energy
The vortex free energy is studied in the random vortex world-surface model of the infrared sector of SU(3) Yang-Mills theory. The free energy of a center vortex extending into two spatial directions, which is introduced into Yang-Mills configurations ...
C. Hoelbling +4 more
core +2 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source

