Results 81 to 90 of about 441,667 (256)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Properties of the Biot–Savart Operator Acting on Surface Currents

open access: yesSIAM Journal on Mathematical Analysis
We investigate properties of the image and kernel of the Biot-Savart operator in the context of stellarator designs for plasma fusion. We first show that for any given coil winding surface (CWS) the image of the Biot-Savart operator is $L^2$-dense in the space of square-integrable harmonic fields defined on a plasma domain surrounded by the CWS.
openaire   +4 more sources

Beyond surface and deep acting: investigating interaction avoidance in coworkers’ daily relationships and its consequences

open access: yesWork & Stress
Research on emotional labour toward coworkers focused on surface acting and deep acting, thereby applying the knowledge on emotional labour in service but neglecting specific features of coworkers’ relationships. Addressing this issue, we develop and test a conceptual model in which surface acting and deep acting are complemented by another behavioural
Shoshan, Hadar Nesher   +2 more
openaire   +5 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Emotional demands, burnout, and mental wellbeing in healthcare, care, and service work: the mediating role of surface acting across age

open access: yesFrontiers in Organizational Psychology
This study examines how emotional demands and surface acting contribute to burnout and mental wellbeing among professionals in healthcare, care, and service roles. A cross-sectional online survey was conducted with 1,506 participants involved in frequent
Tímea Zsuzsanna Popucza   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy