Results 91 to 100 of about 4,580,313 (302)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

From self-assembly to controlled release: synthesis and properties of dynamic imine-based Gemini surfactants for curcumin delivery

Food Chemistry: X
Surfactants based on dynamic covalent bonds have attracted great interest in the past few decades due to the coexistence of covalent and non-covalent bonds.
Wenbo Zhao, Heng Zhang, Wenwen Yu, Fengbo Zhu, Jianjun Xu, Quanxin Xu, Hongwei He, Fuyong Liu, Qiang Zheng   +8 more
doaj   +1 more source

Non-Aqueous Emulsions Stabilised by Nonionic Nonyl Phenol Ethoxylate Reactive Polymerisable Surfactants

International Journal of Electrochemical Science, 2013
A new series of nonionic polymerisable nonyl phenol ethoxylates (NPEs) has been prepared as organic solvent-soluble surfactants in which straight, branched and cyclic alkyls and phenyl acted as solvophilic segment and polyoxyethylene, or maleate chains ...
Amro K.F. Dyab, Ayman M. Atta, Gamal A. EL-Mahdy   +2 more
doaj   +1 more source

Magnetic flux generation and transport in cool stars

, 2011
The Sun and other cool stars harbouring outer convection zones manifest magnetic activity in their atmospheres. The connection between this activity and the properties of a deep-seated dynamo generating the magnetic flux is not well understood.
Barnes, Baumann, Baumann, Berdyugina, Berdyugina, Caligari, Caligari, Charbonneau, Choudhuri, D. Schmitt, Dikpati, Donahue, Donati, D’Silva, E. Işık, Fan, Fan, Fan, Ferriz-Mas, Ferriz-Mas, Ferriz-Mas, Granzer, Hathaway, Holzwarth, Holzwarth, Hoyng, Işık, Işık, Işık, Jouve, M. Schüssler, Montesinos, Moreno-Insertis, Moreno-Insertis, Ossendrijver, Parker, Petit, Petit, Rempel, Rempel, Rüdiger, Schmitt, Schou, Schrijver, Schrijver, Schüssler, Schüssler, Schüssler, Schüssler, Skaley, Snodgrass, Snodgrass, Spruit, Strassmeier, Strassmeier, Strassmeier, van Ballegooijen, Vogt   +57 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Arginine-Derived Cationic Surfactants Containing Phenylalanine and Tryptophan: Evaluation of Antifungal Activity, Biofilm Eradication, Cytotoxicity, and Ecotoxicity

Journal of Xenobiotics
Due to the growing emergence of bacterial and fungal resistance, there is an urgent need for novel antimicrobial compounds. Cationic surfactants are effective antimicrobial agents; however, traditional quaternary ammonium compounds (QACs) are ...
M. Teresa García, M. Carmen Morán, Ramon Pons, Zakaria Hafidi, Elena Bautista, Sergio Vazquez, Lourdes Pérez   +6 more
doaj   +1 more source

Three-dimensional simulations of near-surface convection in main-sequence stars. III. The structure of small-scale magnetic flux concentrations

, 2015
The convective envelopes of cool main-sequence stars harbour magnetic fields with a complex global and local structure. These fields affect the near-surface convection and the outer stellar atmospheres in many ways and are responsible for the observable ...
Beeck, Benjamin, Cameron, Robert H., Reiners, Ansgar, Schüssler, Manfred   +3 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Dimeric Surfactants: Promising Ingredients of Cosmetics and Toiletries

Cosmetics, 2013
Surfactants are an essential ingredient for cosmetic, toiletries and personal care products for enhancing their performance. Dimeric surfactants demonstrate superiority compared to conventional surfactants in all areas of application. Dimeric surfactants
Naveen Kumar, Rashmi Tyagi
doaj   +1 more source

Icequakes coupled with surface displacements for predicting glacier break-off

, 2010
A hanging glacier at the east face of Weisshorn (Switzerland) broke off in 2005. We were able to monitor and measure surface motion and icequake activity for 25 days up to three days prior to the break-off.
Allen, Anifrani, Didier Sornette, Jérome Faillettaz, Kuksenko, Lüthi, Martin Funk, O’Neel, Raymond, Röthlisberger, Sammis, Sornette, Sornette, Sornette   +13 more
core   +1 more source