Results 71 to 80 of about 4,641,442 (292)

Molecular Structure Modulated Trap Distribution and Carrier Migration in Fluorinated Epoxy Resin

Molecules, 2020
Surface charge accumulation on epoxy insulators is one of the most serious problems threatening the operation safety of the direct current gas-insulated transmission line (GIL), and can be efficiently inhibited by the surface modification technology ...
Jin Li, Yufan Wang, Zhaoyu Ran, Hang Yao, Boxue Du, Tatsuo Takada   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Older People’s Attitudes to Road Charging: Are They Distinctive and What are the Implications for Policy? [PDF]

, 2011
In an ageing society older people have a growing influence on politics in general, and potentially on the acceptability of road charging in particular. They face specific types of risk of transport-related social exclusion which may influence their views
Nikitas, Alexandros, Parkhurst, Graham, Erel Avineri, Graham Parkhurst, Avineri, Erel, Alexandros Nikitas   +5 more
core   +1 more source

An Analysis of the Effect of Hall Thruster Plumes on Surface Charging of a Complex Spacecraft Structure

Applied Sciences
This article aims to conduct an in-depth investigation into the environmental impact of Hall thruster plumes on spacecraft surface charging. The non-uniform plasma plume generated by Hall thrusters may trigger charging and discharging effects, making the
Xin Zhang, Wenjing Wang, Chaopin Bai, Yueqiang Sun, Shichen Jiang, Zhihao Yang, Qiang Chen, Lichang Zhang, Liguo Zhang, Zhiliang Zhang, Ziting Wang, Shuai Zhang   +11 more
doaj   +1 more source

Effect of Surface Roughness on Hydrogen-Induced Blister Behavior in Pure Iron

Metals, 2020
The effect of surface roughness on hydrogen-induced blister behavior in pure iron was explored using optical microscopy and microcomputerized tomography.
Xinfeng Li, Yao Wang, Weihong Huang, Jin Zhang, Xubin Wu   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Tribo-electrification and Powder Adhesion Studies in the Development of Polymeric Hydrophilic Drug Matrices [PDF]

, 2015
The generation of tribo-electric charge during pharmaceutical powder processing can cause a range of complications, including segregation of components leading to content uniformity and particle surface adhesion.
Conway, Barbara R, Enes Šupuk, Muhammad Ghori, Šupuk, Enes, Conway, Barbara R., Barbara Conway, Ghori, Muhammad U.   +6 more
core   +1 more source

Surfaces Designed for Charge Reversal

Journal of the American Chemical Society, 2003
We have created surfaces which switch from cationic at pH < 3 to anionic at pH > 5, by attaching aminodicarboxylic acid units to silica and gold substrates. Charge reversal was demonstrated by monitoring the adsorption of cationic dyes (methylene blue and a tetracationic porphyrin) and an anionic sulfonated porphyrin, at a range of pH using UV-vis ...
Matthews, JR, Tuncel, D, Jacobs, R, Bain, C, Anderson, H   +4 more
openaire   +2 more sources

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source