Results 91 to 100 of about 42,354 (265)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
On the Kähler Rank of Compact Complex Surfaces [PDF]
Harvey and Lawson introduced the Kaehler rank and computed it in connection to the cone of positive exact currents of bidimension (1,1) for many classes of compact complex surfaces. In this paper we extend these computations to the only further known class of surfaces not considered by them, that of Kato surfaces.
openaire +4 more sources
Understanding how common soil constituents regulate iron oxide transformation is essential for predicting the stability of co-occurring Pb and As under dynamic conditions.
Xinghua Luo +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Surface complexation modeling of Cu(II) adsorption on mixtures of hydrous ferric oxide and kaolinite
Background The application of surface complexation models (SCMs) to natural sediments and soils is hindered by a lack of consistent models and data for large suites of metals and minerals of interest.
Schaller Melinda S +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Surface complexation model for strontium sorption to amorphous silica and goethite
Strontium sorption to amorphous silica and goethite was measured as a function of pH and dissolved strontium and carbonate concentrations at 25°C. Strontium sorption gradually increases from 0 to 100% from pH 6 to 10 for both phases and requires multiple
Criscenti Louise J +3 more
doaj +1 more source
Eu(III) and Am(III) adsorption on aluminum (hydr)oxide minerals: surface complexation modeling. [PDF]
Satpathy A, Hixon AE.
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Understanding fluoride adsorption from groundwater by alumina modified with alum using PHREEQC surface complexation model. [PDF]
Adu-Boahene F +4 more
europepmc +1 more source

