Results 131 to 140 of about 2,901,641 (329)

The Interplay of Surface Composition, Mineralogy, and Physical Conditions That Affect the Surface Release Processes and Particle Environment of Mercury

open access: yesThe Planetary Science Journal
Mercury has a very tenuous atmosphere starting at the surface, which is referred to as a surface-bound exosphere, where there are no collisions between exospheric particles.
Peter Wurz   +8 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Surface nanostructuring of titanium alloy dental screws by 10 keV Ar+ irradiation

open access: yesResults in Surfaces and Interfaces
The influence of 10 keV Ar+ ion irradiation on the surface topography of Ti–6Al–4V dental screws was investigated. The surface facing the ion beam became uniformly covered with nanoprotrusions, the size of which increased with the ion fluence.
A.E. Ieshkin   +3 more
doaj   +1 more source

A hybrid additive manufacturing platform to create bulk and surface composition gradients on scaffolds for tissue regeneration. [PDF]

open access: yesNat Commun, 2021
Sinha R   +6 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

JWST Thermal Emission of the Terrestrial Exoplanet GJ 1132b

open access: yesThe Astrophysical Journal Letters
We present thermal emission measurements of GJ 1132b spanning 5–12 μ m obtained with the Mid-Infrared Instrument Low-Resolution Spectrometer on the James Webb Space Telescope.
Qiao Xue   +11 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

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