Results 91 to 100 of about 5,064,148 (288)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Surface Graphitized Mesoporous Carbon Surpasses the Conductivity–Porosity Trade‐Off
Advanced ScienceIn carbon engineering, a longstanding trade‐off persists: chemical activation increases surface area but sacrifices conductivity, whereas graphitization enhances conductivity at the expense of porosity.
Juntian Fan +12 more
doaj +1 more source
Fractal and FractionalResistivity is a key parameter in shale reservoir characterization. Diverse micro-pore types and complex conduction mechanisms in shale result in poor accuracy when applying existed conductivity models. Establishing a high-precision conductivity response
Weibiao Xie +5 more
doaj +1 more source
Field investigation of efficient thermal conductivity of snow cover on Spitsbergen
Лëд и снег, 2015 This paper presents results of field investigations of coefficient of efficient thermal conductivity of snow with different structures and densities. Observations were performed in spring of 2013 in the vicinity of meteorological station Barentsburg. The
N. I. Osokin, A. V. Sosnovsky
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Electrodynamics of Carbon Nanotubes with Non-Local Surface Conductivity
Applied SciencesA new framework that can be utilized for the electrodynamics of carbon nanotubes (CNTs) with non-local surface conductivity (spatial dispersion) is presented.
Tomer Berghaus +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source