Results 51 to 60 of about 363,241 (312)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Basin insulator is a critical component of gas-insulated transmission line (GIL) systems. Air gap defects and surface crack defects may form in basin insulators due to casting, installation, or transport processes.
Zhuoran Yang +5 more
doaj +1 more source
Study on creep damage and crack growth for TC11 under complex stress loading
In order to investigate the creep damage and creep crack growth of TC11, we established the finite element model based on ductility exhaustion constitutive model.
doaj +1 more source
Short crack initiation and growth at 600 °C in notched specimens of Inconel718
The natural initiation and growth of short cracks in Inconel®718 U-notch specimens has been studied at 600 °C in air. U notches were introduced through broaching, and hardness traces and optical microscopy on cross-sections through the U notch broaching ...
Connolley, T. +2 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Surface crack and cracks networks in biaxial fatigue
Semi-elliptical fatigue crack growth in 304 L stainless steel, under biaxial loading, was investigated. Compared to those of through-cracks under uniaxial loading, the growth rate of surface cracks is increased by a non-singular compressive stress and reduced by a tensile stress, when R = 0.
Kane, Alexandre, Doquet, Véronique
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Energy radiation of moving cracks
The energy radiated by moving cracks in a discrete background is analyzed. The energy flow through a given surface is expressed in terms of a generalized Poynting vector. The velocity of the crack is determined by the radiation by the crack tip.
A. Karma +46 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Three-Dimensional Surface Crack Growth of Maraging Steel Spherical Pressure Shell
This study focused on the three-dimensional surface crack growth of a spherical pressure shell. Eight maraging steel 18Ni (250) samples were fabricated and tested, and the fatigue crack growth rate curves were obtained.
Yongmei Zhu, Rujun Li, Jiahao Yang
doaj +1 more source

