Results 101 to 110 of about 4,863,941 (314)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
, 2022 Tropical cyclones (TC) transfer kinetic energy to the upper ocean and thus accelerate the ocean mixed layer (OML) currents. However, the quantitative link between near-surface currents and high wind speeds, under extreme weather conditions, remains ...
Guoqiang Liu +15 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Surface currents in the Porsanger fjord in northern Norway [PDF]
, 2016 We describe surface currents in the Porsanger fjord (Porsangerfjorden) located in the European Arctic in the vicinity of the Barents Sea. Our analysis is based on surface current data collected in the summer of 2014 using High Frequency (WERA, Helzel ...
Jankowski, Andrzej +5 more
core +1 more source
Impact of assimilation of absolute dynamic topography on Arctic Ocean circulation
Frontiers in Marine ScienceThe ocean circulation is typically constrained in operational analysis and forecasting systems through the assimilation of sea level anomaly (SLA) retrievals from satellite altimetry. This approach has limited benefits in the Arctic Ocean and surrounding
Gregory C. Smith +8 more
doaj +1 more source
From rays to fields: a conceptual approach to light reflection in metallic mirrors [PDF]
Revista Brasileira de Ensino de FísicaThe reflection of light in mirrors is commonly introduced through geometric optics, emphasizing rays, angles, and image formation. Although effective at a phenomenological level, this approach often obscures the physical origin of the reflected field. In
Fabiana Kneubil
doaj +2 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The response of transformers to geomagnetically induced- like currents [PDF]
, 2014 Includes bibliographical references.This dissertation discusses the development and implementation of a rigorously developed protocol for characterizing and testing transformers with GIC-like currents based on their magnetization curve characteristics ...
Chisepo, Hilary K
core
NektonThe eastern Seram waters are influenced by both the Seram Sea and the Banda Sea. This study aimed to examine variations in wind, surface currents, and sea surface temperature (SST) during 2015, coinciding with the super El Niño event.
Cipta Utama +4 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source