Results 111 to 120 of about 4,863,941 (314)
Remote SensingThe processes of ocean dynamics are complex near the Pearl River Estuary and are not clear due to a lack of abundant observations. The spatial characteristics of the spring sea surface currents in the adjacent waters of the Pearl River Estuary were ...
Haoyue Li +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
On Extreme Surface and Sub-Surface Currents Driven by North Brazil Current Rings Offshore Suriname
, 2018 North Brazil Current Rings (NBCRs) are mesoscale oceanic vortexes (100-500km in diameter) that significantly affect current conditions offshore Suriname and other countries in the Western Equatorial Atlantic.
Rafael V. Schiller, Rosemary B. Smith
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
World Surface Currents From Ship's Drift Observations
, 1980 Over 4 million observations of ship's drift are on file at the U.S. National Oceanographic Data Centre, in Washington, D. C., representing a vast amount of information on ocean surface currents.
Duncan, C. P., Schladow, S. G.
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Salish Sea surface currents: real-time velocities from HF radar [PDF]
, 2018 Ocean Networks Canada has operated Salish Sea CODAR high-frequency (HF) surface radar systems for monitoring surface currents since 2012. The network of antennae continues to grow, with four arrays now deployed in the southern Strait of Georgia, two more
Dewey, Richard +3 more
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Tracking Pelagia noctiluca scyphomedusae by combining modeling and stable isotope approaches
Frontiers in Marine ScienceTrue jellyfish (Cnidaria, Scyphozoa) often appear in large aggregations along the coasts, where they interfere with human activities (tourism, fisheries, power plants).
Isabella D’Ambra +10 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
LONG-TERM OBSERVATIONS OF CURRENTS IN TANABE BAY
, 1983 A series of long-term observations of currents has been carried out at the Tower Station, Shirahama Oceanographic Observatory to find dynamical behaviour of coastal water in TanabeBay.
海象(流れ)観測グループ
core