Results 91 to 100 of about 16,880,130 (352)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Activated Amorphous Carbon With High-Porosity Derived From Camellia Pollen Grains as Anode Materials for Lithium/Sodium Ion Batteries

Frontiers in Chemistry, 2018
Carbonaceous anode materials are commonly utilized in the energy storage systems, while their unsatisfied electrochemical performances hardly meet the increasing requirements for advanced anode materials.
Kaiqi Xu, Yunsha Li, Yunsha Li, Jiawen Xiong, Xing Ou, Wei Su, Guobin Zhong, Chenghao Yang   +7 more
doaj   +1 more source

Nucleation-controlled growth of superior lead-free perovskite Cs3Bi2I9 single-crystals for high-performance X-ray detection

Nature Communications, 2020
Organic-inorganic hybrid halide perovskites have been emerged as promising candidates for X-ray detectors while toxicity and instability are known issues. Here, Zhang et al.
Yunxia Zhang, Yucheng Liu, Zhuo Xu, Haochen Ye, Zhou Yang, Jiaxue You, Ming Liu, Yihui He, Mercouri G. Kanatzidis, Shengzhong (Frank) Liu   +9 more
doaj   +1 more source

Non-universal equilibrium crystal shape results from sticky steps

, 2011
The anisotropic surface free energy, Andreev surface free energy, and equilibrium crystal shape (ECS) z=z(x,y) are calculated numerically using a transfer matrix approach with the density matrix renormalization group (DMRG) method.
Akutsu N, Akutsu N, Akutsu Y, Akutsu Y Akutsu N Yamamoto T, Andreev A F, Andreev A F, Avron J E, Babkin A V, Baxter R J, Frank F C, Frank F C, Gallet G F, Hieida Y, Kern R, Krug J, Landau L D, Leamy H J, Lieb E, Messia A, Natsume Y, Noriko Akutsu, Nowicki M, Nowicki M, Nozières P, Ohachi T, Ookawa A, Pavlovska A, Peschel I, Pokrovskii V L, Toschev S, Truong T T, Uwaha M, van Beijeren H, von Laue M, Wulff G, Yamamoto T Akutsu Y   +35 more
core   +1 more source

Surface plasmon modes and the Casimir energy [PDF]

, 2005
We show the influence of surface plasmons on the Casimir effect between two plane parallel metallic mirrors at arbitrary distances. Using the plasma model to describe the optical response of the metal, we express the Casimir energy as a sum of ...
A. Lambrecht, C. Genet, C. Itzykson, E. M. Lifshitz, F. Intravaia, G. Barton, H. B. G. Casimir   +6 more
core   +4 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

On the spreading of impacting drops [PDF]

, 2016
The energy budget and dissipation mechanisms during droplet impact on solid surfaces are studied numerically and theoretically. We find that for high impact velocities and negligible surface friction at the solid surface (i.e.
Lohse, Detlef, Sun, Chao, Visser, Claas Willem, Wildeman, Sander   +3 more
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Continuum Surface Energy from a Lattice Model

, 2014
We investigate connections between the continuum and atomistic descriptions of deformable crystals, using certain interesting results from number theory. The energy of a deformed crystal is calculated in the context of a lattice model with general binary
A. Barvinok, A. Braides, A. Eichler, A. Ivic, A. V. Shapeev, B. Dacorogna, C. Herring, C. Mora-Corral, F. Theil, G. A. Pick, I. Bárány, I. Fonseca, J. D. Sally, J. E. Reeve, J. G. Van der Corput, K.-M. Tsang, M. Beck, M. N. Huxley, P. Rosakis, X. Blanc   +19 more
core   +1 more source

Secondary-Structure Design of Proteins by a Backbone Torsion Energy [PDF]

, 2005
We propose a new backbone-torsion-energy term in the force field for protein systems. This torsion-energy term is represented by a double Fourier series in two variables, the backbone dihedral angles phi and psi.
Berendsen H. J. C., Blanco F. J., Cornell W. D., Duan Y., Garcia A. E., Honda S., Iwaoka M., Jorgensen W. L., Kabsch W., Kaminski G. A., Kamiya N., Kirkpatrick S., Kobayashi N., Kraulis P. J., MacKerell A. D., MacKerrell A. D., Merritt E. A., Mitsutake A., Némethy G., Osterhout J. J., Qiu D., Ramachandran G. N., Sakae Y., Sakae Y., Sakae Y., Shoemaker K. R., Simmerling C., Still W. C., Wang J., Yoda T., Yoda T.   +30 more
core   +2 more sources