Results 91 to 100 of about 1,523,806 (318)
Organic-inorganic hybrid halide perovskites have been emerged as promising candidates for X-ray detectors while toxicity and instability are known issues. Here, Zhang et al.
Yunxia Zhang +9 more
doaj +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The International Urban Energy Balance Models Comparison Project: First Results from Phase 1
A large number of urban surface energy balance models now exist with different assumptions about the important features of the surface and exchange processes that need to be incorporated.
Best, MJ +94 more
core +1 more source
Fundamental Ion-Surface Interactions in Plasma Thrusters [PDF]
Ion thrusters offer the potential to enable many future interplanetary robotic missions presently under consideration by NASA. To realize the benefits offered by these low thrust devices, the sputtering mechanisms that are responsible for the ...
Kolasinski, Robert David
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The global energy transition and decarbonization drive are putting pressure on oil demand while shale has unlocked abundant resources. The global context forces African petroleum producers to adapt or become uncompetitive. The coronavirus pandemic (COVID-
African Energy Chamber
core
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The role of photonics in energy [PDF]
A.F.N. acknowledges support from the Fundação de Amparo a Pesquisa no Estado de São Paulo (FAPESP) and the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) of Brazil. D.O’C. acknowledges support from the U.S.
O'Carroll, D.M. +10 more
core +1 more source
Under prolonged high‐voltage cycling, single‐crystalline Ni‐rich cathodes are prone to severe transition metal dissolution, irreversible phase transformations, and reduced structural stability, which significantly hinder their practical application ...
Youqi Chu +9 more
doaj +1 more source

