Results 101 to 110 of about 16,880,130 (352)

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

The Surface Energy Balance System (SEBS) for estimation of turbulent heat fluxes

open access: yes, 2002
. A Surface Energy Balance System (SEBS) is proposed for the estimation of atmospheric turbulent fluxes and evaporative fraction using satellite earth observation data, in combination with meteorological information at proper scales.
Z. Su
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Constructing Stable Sub/Surface Structure to Boost Superior Cyclabilities of Single‐Crystalline Ni‐Rich Cathode

open access: yesAdvanced Science
Under prolonged high‐voltage cycling, single‐crystalline Ni‐rich cathodes are prone to severe transition metal dissolution, irreversible phase transformations, and reduced structural stability, which significantly hinder their practical application ...
Youqi Chu   +9 more
doaj   +1 more source

Spontaneous graphitization of ultrathin cubic structures: A computational study

open access: yes, 2014
Results based on {\em ab initio} density functional calculations indicate a general graphitization tendency in ultrathin slabs of cubic diamond, boron nitride, and many other cubic structures including rocksalt.
Kvashnin, Alexander G.   +3 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Thermal desorption of ammonia from crystalline forsterite surfaces

open access: yes, 2015
The thermal desorption of ammonia (NH$_3$) from single crystal forsterite (010) has been investigated using temperature-programmed desorption. The effect of defects on the desorption process has been probed by the use of a rough cut forsterite surface ...
Suhasaria, T.   +2 more
core   +1 more source

Particle Engineering in Pharmaceutical Solids Processing: Surface Energy 
Considerations

open access: yesCurrent pharmaceutical design, 2015
During the past 10 years particle engineering in the pharmaceutical industry has become a topic of increasing importance. Engineers and pharmacists need to understand and control a range of key unit manufacturing operations such as milling, granulation ...
Daryl R. Williams
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Enhanced hydrogen evolution reaction activity through samarium-doped nickel phosphide (Ni2P) electrocatalyst

open access: yesScientific Reports
Hydrogen evolution reaction (HER) stands out among conventional hydrogen production processes by featuring excellent advantages. However, the uncompetitive production cost due to the low energy efficiency has hindered its development, necessitating the ...
Ali Shahroudi, Sajjad Habibzadeh
doaj   +1 more source

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