Results 91 to 100 of about 8,238,647 (329)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Journal of Materials Research and Technology, 2020 In this paper, the effect of shot peening and cryogenic turning on the surface morphology of the metastable austenitic stainless steel AISI 347 was investigated.
Hendrik Hotz +5 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Effect of machining-induced harden layer on wear resistance of Type316L austenitic stainless steel
Nihon Kikai Gakkai ronbunshuIn order to clarify the effect of surface hardening layers induced during machining processes such as cutting and grinding on the wear resistance of austenitic stainless steel SUS316L, a surface hardening layer was intentionally induced on SUS316L ...
Naoaki NAGAISHI +2 more
doaj +1 more source
Anisotropic yield functions in a co-rotating reference frame [PDF]
, 2000 In metal forming simulations large deformations are often treated based on objective formulations. Large rotations are accounted for by rotating the stress tensor or approximating the rotation by some integration rule for the rate of rotation.
Boogaard, A.H. van den +2 more
core +1 more source
Size-dependent mechanical properties of molybdenum nanopillars [PDF]
, 2008 We report the deformation behavior of single crystalline molybdenum nanopillars in uniaxial compression, which exhibits a strong size effect called the “smaller is stronger” phenomenon.
Greer, Julia R., Kim, Ju-Young
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Surface Hardening of Tungsten Heavy Alloys
Scripta Materialia, 1997 Tungsten-based heavy alloys are produced by sintering from elemental W, Ni, Fe and Cu powder mixtures, where the tungsten content is in the range 80--98 weight%. The alloys, however, show relatively poor surface properties such as wear and corrosion resistance.
Eroglu, S, Ekren, H, Baykara, T
openaire +2 more sources
A Nonvolume Preserving Plasticity Theory with Applications to Powder Metallurgy [PDF]
, 1983 A plasticity theory has been developed to predict the mechanical response of powder metals during hot isostatic pressing. The theory parameters were obtained through an experimental program consisting of hydrostatic pressure tests, uniaxial compression ...
Cassenti, B. N.
core +1 more source
Numerical simulation of a class of models that combine several mechanisms of dissipation: fracture, plasticity, viscous dissipation [PDF]
, 2014 We study a class of time evolution models that contain dissipation mech- anisms exhibited by geophysical materials during deformation: plasticity, viscous dissipation and fracture. We formally prove that they satisfy a Clausius-Duhem type inequality.
Bonnetier, Eric +3 more
core +4 more sources