Results 111 to 120 of about 8,238,647 (329)
A Potential Function Derivation of a Constitutive Equation for Inelastic Material Response [PDF]
, 1983 Physical and thermodynamic concepts are used to develop a potential function for application to high temperature polycrystalline material response. Inherent in the formulation is a differential relationship between the potential function and constitutive
Elfoutouh, N. A., Stouffer, D. C.
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
LOW-TEMPERATURE SURFACE HARDENING FOR DIAMOND TOOLS
Наука и техника, 2009 The structure and properties of cutting diamond tools subjected to thermo-hydro-chemical treatment are examined in the paper. The process involves a chemical treatment of tools in a specially prepared aqueous suspension of oxides Ti, Mo and other ...
A. A. Shmatov, O. O. Smilovenko
doaj
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Laser Surface Hardening of 51CrV4 Steel
The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2005 The work presents the surface changes in microstructure and properties by quenching the 51CrV4 steel from liquid and solid phase, using a CO2 continue laser wave with 900W power.
Sanda Maria LEVCOVICI +1 more
doaj
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Analysis of ultra low cycle fatigue problems with the barcelona plastic damage model [PDF]
, 2013 This paper presents a plastic formulation based on the Barcelona plastic damage model ([1], [2]) capable of predicting the material failure due to Ultra Low Cycle Fatigue.
Barbat Barbat, Horia Alejandro +3 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
DEFORMATION BEHAVIOR OF NANO/MICRO REINFORCED PMMA [PDF]
, 2010 Práce sleduje vliv velikosti částic na elastický modul a deformační chování za mezí kluzu. Bylo pozorováno, že jak elastická oblast, tak oblast za mezí kluzu ukazuje silnou závislost chování na velikosti částic.
Recman, Lukáš
core