Results 61 to 70 of about 8,238,647 (329)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The influence of laser hardening on wear in the valve and valve seat contact [PDF]
, 2009 In internal combustion engines it is important to manage the wear in the valve and valve seat contact in order to minimise emissions and maximise economy.
H. Taylor +9 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Loading Surface in the Course of Mechanical- Thermal Treatment and Steady-State Creep of Metals [PDF]
, 2013 : Kinetics of the loading surface of a material gives precious information on the level of the hardening of the material. This paper is concerned with the evolution of the loading surface during successive actions, such as: (i) plastic deformation, (ii)
Ruszinkó, Endre
core
Cosmic Rays in a Galactic Breeze
, 2017 Motivated by the discovery of the non-thermal Fermi bubble features both below and above the Galactic plane, we investigate a scenario in which these bubbles are formed through Galacto-centric outflow. Cosmic rays (CR) both diffusing and advecting within
Giacinti, Gwenael, Taylor, Andrew M.
core +1 more source
An experimental study of the effect of high-pressure water jet assisted turning (HPWJAT) on the surface integrity [PDF]
, 2011 This study deals with the effect of High-Pressure Water Jet Assisted Turning (HPWJAT) of austenitic stainless steels on chip shape and residual stresses. The machining of the austenitic stainless steels represents several difficulties. Recently, research
HABAK, Malek, LEBRUN, Jean-Lou
core +4 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Journal of Harbin University of Science and Technology, 2019 Based on process parameter optimization results, the influence laws and reasons of different cutting environments and cutting parameters(cutting speed, feed), process parameter (jet temperature, cutting oil amount) under cryogenic minimum quantity ...
ZHANG Huiping +3 more
doaj +1 more source
Damage of the Surface Layer Gears in Grinding Process. [PDF]
, 2013 The influence of the grinding process on the condition of the surface layer (SL) obtained by the treatment of the gear with grinding wheels Al2O3, CBN, GF, SG, alloy steels with different parameters of the grinding process and the type of cooling liquid –
Wlazło, Jakub, Wójcik, Ryszard
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source