Results 61 to 70 of about 4,514,829 (351)

State of Ammonium Hydrosulfide (NH4SH) Salt on Icy Bodies in the Trans-Neptunian Space

open access: yesThe Astrophysical Journal
Ammonium hydrosulfide (NH _4 SH) is expected to be widespread on trans-Neptunian objects (TNOs), considering the predicted high abundance of hydrogen sulfide (H _2 S) in the presolar nebula and the detection of ammonia (NH _3 ) on TNOs such as Charon and
Chaojiang Zhang   +4 more
doaj   +1 more source

Inderwater noise characteristics of TINRO-Center’s reseach vessels

open access: yesИзвестия ТИНРО, 2014
Underwater noise radiated by two medium-tonnage research vessels of Pacific Fish. Res. Center (TINRO) belonged to the same project «Atlantic-833» (RV TINRO and Professor Kaganovsky) is measured by a calibrated hydrophone system.
Michail Yu. Kuznetsov   +2 more
doaj   +1 more source

NAFO/ICES Pandalus Assessment Group Meeting, [22–30 October 2008 ICES Headquarters, Copenhagen, Denmark] [PDF]

open access: yes, 2008
Contributors: Carsten Hvingel, Guldborg Søvik and Trond ...
ICES
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Optical Spectroscopy of the Uranian Moons from Equinox to Northern Summer

open access: yesThe Planetary Science Journal
We present an analysis of ground-based visible and near-infrared wavelength (VIS, ∼0.4–0.9 μ m) reflectance spectra of the four largest Uranian satellites, utilizing observations with multiple telescopes, collected near Uranian equinox and in northern ...
Riley A. DeColibus   +5 more
doaj   +1 more source

Experimental investigation of O2 diffusion and entrapment in interstellar amorphous solid water

open access: yesAstronomy & Astrophysics
Context. Interstellar ices are mainly composed of amorphous solid water (ASW) containing small amounts of hypervolatiles, such as O2, whose diffusion-limited reactions play a key role in space chemistry.
Coulaud L., Santos J. C., Chuang K.-J.
doaj   +1 more source

Report of the Planning Group on Northeast Atlantic Pelagic Ecosystem Surveys (PGNAPES) [PDF]

open access: yes, 2006
The present report was prepared on the Planning Group on Northeast Atlantic Pelagic Ecosystem Surveys (PGNAPES) in Reykjavik, Iceland 15–18 August 2006 and contains the results of the acoustic, hydrographic, plankton and fish sampling from two ...
ICES
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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