Results 51 to 60 of about 1,347,538 (354)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Surface Integrity Characteristics and Fatigue Failure Mechanism of Carburized M50NiL Steel

Journal of Aeronautical Materials, 2017
The surface integrity of carburized M50NiL steel was studied by optical microscopy, scanning electron microscopy (SEM), atomic force microscopy (AFM), microhardness tester and residual stress tester.
LOU Yanzhi, LI Chunzhi, LI Xudong, XIE Xiaochang, ZHAO Zhenye   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Experimental investigation of cutting parameters dependence in diamond turning of monocrystalline silicon

AIMS Materials Science, 2019
The machinability of brittle materials is strongly dependent on machining conditions. In the present work, we perform ultra-precision single point diamond turning experiments of monocrystalline Si(100) using diamond cutting tools.
Lu Liao, Guo Li, Junjie Zhang
doaj   +1 more source

Surface Integrity of AISI 52100 Bearing Steel after Robot-Based Machine Hammer Peening

Journal of Manufacturing and Materials Processing, 2020
AISI 52100 steel is often used as material for highly loaded rolling bearings in machine tools. An improved surface integrity, which can be achieved by means of mechanical surface layer finishing, can avoid premature failure.
Robby Mannens, Lars Uhlmann, Felix Lambers, Andreas Feuerhack, Thomas Bergs   +4 more
doaj   +1 more source

Characterising the impact of surface integrity on the fatigue behaviour of a shot-peened connecting rod [PDF]

, 2014
The present study focuses on analysing and modelling the influence on fatigue behaviour of the surface of a hot-forged C70 connecting rod which undergoes a shot-blasting treatment.
GERIN, Benjamin, MOREL, Franck, PESSARD, Etienne, VERDU, Catherine   +3 more
core   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Optimization of hot press forging parameters in direct recycling of aluminium chip (AA 6061) [PDF]

, 2014
This study introduces a new approach of direct recycling using the hot press forging process that eliminates the two intermediate processes of cold-compact and pre-heating. This method leads to low energy consumption without intervening the metallurgical
Ahmed, Rizwan, Al-Ramadan, Baqer, Aldosary, Adel S., Jamal, Arshad, Rahman, Rahisham Abd, Ullah, Rahmat   +5 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source