Results 101 to 110 of about 4,267,348 (351)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Coupled influence of tectonics, climate, and surface processes on landscape evolution in southwestern North America. [PDF]

Nat Commun, 2022
Bahadori A, Holt WE, Feng R, Austermann J, Loughney KM, Salles T, Moresi L, Beucher R, Lu N, Flesch LM, Calvelage CM, Rasbury ET, Davis DM, Potochnik AR, Ward WB, Hatton K, Haq SSB, Smiley TM, Wooton KM, Badgley C.   +19 more
europepmc   +1 more source

Anomalous Roughness in Dimer-Type Surface Growth

, 2000
We point out how geometric features affect the scaling properties of non-equilibrium dynamic processes, by a model for surface growth where particles can deposit and evaporate only in dimer form, but dissociate on the surface. Pinning valleys (hill tops)
A. L. Barabási, G. I. Menon, H. Hinrichsen, H. Takayasu, Hyunggyu Park, Jae Dong Noh, M. den Nijs, M. H. Kim, M. Kardar, Marcel den Nijs, N. Inui, P. Grassberger, T. Halpin-Healy, U. Alon, V. Privman, W. Hwang   +15 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Surface Condition Evolution and Fatigue Evaluation after Different Surface Processes for TiAl₄₇Cr₂Nb₂ Alloy. [PDF]

Materials (Basel), 2022
Yu W, Yin Y, Zhou J, Xu Q, Feng X, Nan H, Zuo J, Wang X, Ding X.   +8 more
europepmc   +1 more source

Duplex and superduplex stainless steels: microstructure and properties evolution by surface modification processes [PDF]

, 2019
The paper presents an overview of diffusion surface treatments, especially nitriding processes, applied to duplex and superduplex stainless steels in the last five years. Research has been done mainly to investigate different nitriding processes in order
Biserova Tahchieva, Alisiya, Cabrera Marrero, José M., Llorca Isern, Núria   +2 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Urinary biomarkers for assessment of human exposure to monomeric aryl phosphate flame retardants

Environment International, 2019
While monomeric aryl organophosphate flame retardants (m-aryl-OPFRs) are used worldwide in a variety of consumer products, specific biomarkers for epidemiologic studies are lacking.
Fanrong Zhao, Qiyue Kang, Xiaohua Zhang, Jiaying Liu, Jianying Hu   +4 more
doaj   +1 more source

Improved sampling and validation of frozen Gaussian approximation with surface hopping algorithm for nonadiabatic dynamics

, 2016
In the spirit of the fewest switches surface hopping, the frozen Gaussian approximation with surface hopping (FGA-SH) method samples a path integral representation of the non-adiabatic dynamics in the semiclassical regime.
Lu, Jianfeng, Zhou, Zhennan
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source