Results 101 to 110 of about 9,664,885 (256)
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Title from home page (viewed on Aug. 23, 2006).; "Prepared by State of Ohio Environmental Protection Agency, Division of Surface Water ..."--PDF t.p.; "June 28, 2004."; Harvested from the web on 8/23 ...
Ohio EPA. Division of Surface Water.
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Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Laser surface engineering : processes and applications /
Lasers can alter the surface composition and properties of materials in a highly controllable way, which makes them efficient and cost-effective tools for surface engineering. This book provides an overview of the different techniques, the laser-material
Lawrence, J.,editor. +2 more
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Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Recent studies reveal asymmetric land surface temperature (LST) responses to forest gain and loss, yet the role of underlying land cover conversions (LCC) remains unclear.
Yuehan Yu +5 more
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Global warming is dramatically altering the plant phenology of terrestrial ecosystem and thus has caused significant effects on the terrestrial carbon cycle. Many studies have investigated the relationships between the spring phenological changes and the
Zhiying Xie +4 more
doaj +1 more source

