Results 101 to 110 of about 578,287 (295)

Optimization of fast melting olanzapine tablets using solid dispersion and response surface methodology

Journal of Applied Pharmaceutical Research
Background: Olanzapine is a poorly water-soluble, anti-psychotic drug that belongs to the class of thiobenzodiazepines, which has a bioavailability of 60 – 65%.
Sundaramoorthi Revathi, Pavadai Anitha, Sathappan Jenifer, Sivakumar Senthil Rajan   +3 more
doaj   +1 more source

Enhancement of Aqueous Solubility and Dissolution of Celecoxib through Phosphatidylcholine-Based Dispersion Systems Solidified with Adsorbent Carriers

Pharmaceutics, 2018
This study aimed to design phosphatidylcholine (PC)-based solid dispersion (SD) systems for enhancing the apparent aqueous solubility and dissolution of celecoxib (CLC), a selective cyclooxygenase-2 inhibitor with a highly hydrophobic property.
Kanghee Jo, Jae Min Cho, Hyunjoo Lee, Eun Kyung Kim, Hong Chul Kim, Hyeongmin Kim, Jaehwi Lee   +6 more
doaj   +1 more source

Characterization of Nitinol Produced by Laser Powder Bed Fusion for Mechanical Metamaterial Applications

Advanced Engineering Materials, EarlyView.
Stabilization of L‐PBF Ni50.7Ti49.3 under low‐cycle loading was investigated. Recoverable strain after cycling was dependent on the amount of applied load. Recovery ratio was 53.4% and 35.1% at intermediate and high load, respectively. The maximum total strain reached 10.3% at a high load of 1200 MPa.
Ondřej Červinek, Jakub Hurník, Miroslav Šmíd, Ondřej Zobač, Melanie Todt, Daniel Koutný   +5 more
wiley   +1 more source

Fast accretion of small planetesimals by protoplanetary cores

, 2003
We explore the dynamics of small planetesimals coexisting with massive protoplanetary cores in a gaseous nebula. Gas drag strongly affects the motion of small bodies leading to the decay of their eccentricities and inclinations, which are excited by the ...
Greenberg J. M., Hasegawa M., Ida S., R. R. Rafikov, Weidenschilling S. J.   +4 more
core   +2 more sources

Reduction of Oxide Inclusions During the High‐Frequency Welding of Steel via a Nonthermal Ar/H2 Plasma Jet

Advanced Engineering Materials, EarlyView.
High‐frequency (HF) welding of steel is limited by oxide inclusions that degrade weld quality. This study demonstrates, for the first time, the integration of a nonthermal Ar/H2 dielectric barrier discharge (DBD) plasma jet into HF welding. Local plasma treatment provides effective shielding and in‐situ oxide reduction, resulting in markedly fewer and ...
Viktor Udachin, Lienhard Wegewitz, René Gustus, Henning Wiche, Wolfgang Maus‐Friedrichs   +4 more
wiley   +1 more source

Studies in Dissolution Enhancement of Ezetimibe by Solid Dispersions in Combination with a Surface Adsorbent

Dissolution Technologies, 2011
The aim of this investigation was to improve the dissolution properties of the water-insoluble drug ezetimibe (EZE) and potentially improve bioavailability. A combination of melt and adsorption techniques was employed for the preparation of solid dispersions.
Komal R. Parmar, Sunny R. Shah, Navin R. Sheth   +2 more
openaire   +1 more source

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

Advanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora, Tales V. Lisbôa, Axel Spickenheuer, Rogério J. Marczak, Jakson M. Vassoler   +4 more
wiley   +1 more source

Electrostatic Precipitation of Submicron Particles in a Molten Carrier

Pharmaceutics, 2019
Recently, submicron particles have been discussed as a means to increase the bioavailability of poorly water-soluble drugs. Separation of these small particles is done with both fibre and membrane filters, as well as electrostatic precipitators.
Adrian Dobrowolski, Damian Pieloth, Helmut Wiggers, Markus Thommes   +3 more
doaj   +1 more source

Handbook of Establishing and Maintaining Oxygen‐Free Atmospheres

Advanced Engineering Materials, EarlyView.
This study presents a practical framework for creating oxygen‐free atmospheres at ambient pressure using silane‐doped inert gases. The results show that ultra‐low oxygen levels and strongly reduced water content can be achieved through controlled silane dosing, drying systems, and sensor monitoring.
Sascha Jan Zimmermann, René Gustus, Lienhard Wegewitz, Wolfgang Maus‐Friedrichs   +3 more
wiley   +1 more source

Superhydrophobization of hydrophilic silica via solid phase reaction enhances dispersion in deproteinized natural rubber

Discover Chemistry
Superhydrophobic silica is crucial for many industries due to its outstanding water repellency and broad application potential. These materials are defined by water contact angles above 150° and very low sliding angles, allowing droplets to roll off ...
Dai-Luat Tran, Manh-Thang Tran, Trung-Nghia Phan   +2 more
doaj   +1 more source