Results 101 to 110 of about 1,194,493 (356)
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
Summary: Cells can achieve internal organization by exploiting liquid-liquid phase separation to form biomolecular condensates. Here we focus on the surface properties of condensates composed of two multivalent associative polymers held together by one ...
Andrew G.T. Pyo+2 more
doaj
Surface tension of small bubbles and droplets and the cavitation threshold [PDF]
In this paper, using an unified approach, estimates are given of the magnitude of the surface tension of water for planar and curved interfaces in the pairwase interaction approximation based on the Lennard-Jones potential. It is shown that the surface tensions of a bubble and droplet have qualitatively different dependences on the curvature of the ...
arxiv
Interface roughening with nonlinear surface tension
Using stability arguments, this Brief Report suggests that a term that enhances the surface tension in the presence of large height fluctuations should be included in the Kardar-Parisi-Zhang equation.
Barbara Drossel+19 more
core +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
The study presents the mechanical and in situ sensing performance of digital light processing‐enabled 2D lattice nanocomposites under monotonic tensile and repeated cyclic loading, and provides guidelines for the design of architectures suitable for strain sensors and smart lightweight structures.
Omar Waqas Saadi+3 more
wiley +1 more source
Equilibria of Pendant Droplets: Spatial Variation and Anisotropy of Surface Tension [PDF]
An example of capillary phenomena commonly seen and often studied is a droplet of water hanging in air from a horizontal surface. A thin capillary surface interface between the liquid and gas develops tangential surface tension, which provides a balance of the internal and external pressures.
arxiv
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion
Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal+5 more
wiley +1 more source