Results 131 to 140 of about 3,615,523 (297)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Thermal Modification Intensity of Heat-treated Poplar Wood. Part 2: Characterization and Predication from Outside to Core Layers

Drvna Industrija
Based on the previous study of the heat-treated wood at 0-3 mm surface layer, this study focuses on the transition of thermal modification intensity on 160-220 °C heat-treated poplar from surface to core layers.
Yang Li, Tao Yao, Yong Zhu, Shengquan Liu, Zuju Shu, Redžo Hasanagić, Fathi Leila, Demiao Chu   +7 more
doaj   +1 more source

Shear Bond Strength of Lithium Disilicate Bonded with Various Surface-Treated Titanium. [PDF]

Int J Dent, 2022
Amornwichitwech L, Palanuwech M.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Bonding Performance of Surface-Treated Zirconia Cantilevered Resin-Bonded Fixed Dental Prostheses: In Vitro Evaluation and Finite Element Analysis. [PDF]

Materials (Basel), 2023
Malgaj T, Papšík R, Abram A, Kocjan A, Jevnikar P.   +4 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Evaluation of the Impact of Different Surface Treatments on Implant Surface: An In Vitro Study

Journal of Pharmacy and Bioallied Sciences
AimThe current study was conducted to assess the effects of various surface treatments on the implant surface. Materials and MethodsA total of 45 dental implants measuring 16 mm in length and 5 mm in diameter were used, along with the appropriate ...
Subramanian Deepa, Mathew Joel, Mailankote Shilpa, Almuraikhi Turki, Daghriri Alhussain   +4 more
doaj   +1 more source

Additive effectiveness of acrylonitrile-co-methallyl sulfonate surface-treated membranes in the treatment of pneumonia: A propensity score-matched retrospective cohort study. [PDF]

Artif Organs, 2023
Hayashi K, Sasabuchi Y, Matsui H, Nakajima M, Ohbe H, Fushimi K, Ono K, Yasunaga H.   +7 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Long-term evaluation of the prognosis of super hydrophilic surface treated CA implants: a retrospective clinical study. [PDF]

BMC Oral Health, 2022
Kim MJ, Kim IH, Chang NH, Kim YK.
europepmc   +1 more source