Results 71 to 80 of about 1,705,391 (284)
Porewater salinity reveals past lake-level changes in Lake Van, the Earth’s largest soda lake
Scientific Reports, 2017 In closed-basin lakes, sediment porewater salinity can potentially be used as a conservative tracer to reconstruct past fluctuations in lake level. However, until now, porewater salinity profiles did not allow quantitative estimates of past lake-level ...
Yama Tomonaga +12 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
A Physically Based Spatial Expansion Algorithm for Surface Air Temperature and Humidity
Advances in Meteorology, 2013 An algorithm was developed to expand the surface air temperature and air humidity to a larger spatial domain, based on the fact that the variation of surface air temperature and air humidity is controlled jointly by the local turbulence and the ...
Hongbo Su +7 more
doaj +1 more source
Remote Sensing, 2015 Using National Oceanographic and Atmospheric Administration/Advanced Very High Resolution Radiometer (NOAA/AVHRR) and Climatic Research Unit (CRU) climate datasets, we analyzed interannual trends in the growing-season Normalized Difference Vegetation ...
Bo Qu +3 more
doaj +1 more source
Adsorption of Arsenic from Water Using Aluminum-Modified Food Waste Biochar: Optimization Using Response Surface Methodology [PDF]
, 2022 Sayed Q. Hashimi +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Advances in Meteorology, 2016 This paper investigates reference evapotranspiration (ET0) changes, sensitivities to and contributions of meteorological factors in the Heihe River Basin (arid and inland region).
Chaoyang Du +3 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Hydrochemical and Isotopic Explanations of the Interaction between Surface Water and Groundwater in a Typical-Desertified Steppe of Northern China [PDF]
, 2023 Jing Jin +4 more
openalex +1 more source