Results 111 to 120 of about 316,671 (311)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Geometry of branched minimal surfaces of finite index

Advanced Nonlinear Studies
Given I,B∈N∪{0} $I,B\in \mathbb{N}\cup \left\{0\right\}$ , we investigate the existence and geometry of complete finitely branched minimal surfaces M in R3 ${\mathbb{R}}^{3}$ with Morse index at most I and total branching order at most B. Previous works
Meeks William H., Pérez Joaquín
doaj   +1 more source

Elaboration de plateformes biomimétiques à base de dopamine pour la fonctionnalisation du titane Elaboration of biomimetic dopamine platforms for the functionalization of titanium surfaces

MATEC Web of Conferences, 2013
L'étude concerne la fonctionnalisation de surfaces à base de titane à partir d'une ancre chimique biomimétique modifiable chimiquement, la dopamine, dans le but de concevoir des biomatériaux utilisables en tant que dispositifs implantables.
Laure William, Zobrist Cédric, Lyskawa Joël, Fournier David, Woisel Patrice   +4 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A new family of surfaces of general type with K-2=7 and p(g)=0

, 2013
We construct a new family of smooth minimal surfaces of general type with K-2 = 7 and p(g) = 0. We show that a surface in this family has ample canonical divisor and birational bicanonical morphism.
Chen, Yifan
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Generalized Burniat Type surfaces and Bagnera-de Franchis Varieties

, 2015
In this article we construct three new families of surfaces of general type with pg = q = 0,K2 = 6, and seven new families of surfaces of general type with pg = q = 1,K2 = 6, realizing 10 new fundamental groups.
Frapporti Davide, Catanese Fabrizio, Bauer I., Catanese F., Bauer Ingrid, Frapporti D.   +5 more
core  

Inactivation of murine norovirus on a range of copper alloy surfaces is accompanied by loss of capsid integrity

, 2015
Norovirus is one of the most common causes of acute viral gastroenteritis. The virus is spread via the fecal-oral route, most commonly from infected food and water, but several outbreaks have originated from contamination of surfaces with infectious ...
Summersgill, Emma N., Keevil, C William, Warnes, Sarah L.   +2 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

On algebraic surfaces of general type with negative c2

, 2014
We prove that for any prime number $p\ge 3$, there exists a positive number $κ_p$ such that $χ(\mathcal{O}_X)\ge κ_pc_1^2$ holds true for all algebraic surfaces $X$ of general type in characteristic $p$. In particular, $χ(\mathcal{O}_X)>0$. This answers a question of N. Shepherd-Barron when $p\ge 3$.
openaire   +3 more sources