Results 121 to 130 of about 316,671 (311)

Deformation of canonical morphisms and the moduli of surfaces of general type

open access: yes, 2010
In this article we study the deformation of finite maps and show how to use this deformation theory to construct varieties with given invariants in a projective space.
Gallego Rodrigo, Francisco Javier   +5 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Broadband Operation of Binary Metasurfaces: Limitations and Perspectives

open access: yesIEEE Access
In this paper, physical prerequisites of the broadband operation of reflective intelligent surfaces (RIS) implemented as periodically non-uniform metasurfaces (MSs) of binary type are elucidated. The general relation for the maximal operational band of a
Constantin R. Simovski, Javad Shabanpour
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Group representations and canonical surfaces of very high degree

open access: yes, 2017
Given a surface $S$ of general type, we denote by d the degree of the canonical image. d is bounded by the canonical volume $K^2$, and by the BMY inequality we have $d \leq 9 \chi$. In practice, what is the maximum $d$ for $p_g=4,5,6$?
Catanese, Fabrizio
core  

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

On the hyperbolicity of surfaces of general type with small $c_1 ^2$

open access: yes, 2012
25 pages.Surfaces of general type with positive second Segre number $s_2:=c_1^2-c_2>0$ are known by results of Bogomolov to be quasi-hyperbolic i.e. with finitely many rational and elliptic curves. These results were extended by McQuillan in his proof of
Roulleau, Xavier   +3 more
core  

The classification of surfaces of general type with nonbirational bicanonical map

open access: yes, 2007
We classify surfaces of general type whose bicanonical map factors through a rational map of degree 2 to a rational or ruled surface. We prove that if such a surface has no pencil of genus 2 curves, then it is the smooth minimal model of a double plane ...
Giuseppe Borrelli
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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