Results 91 to 100 of about 316,671 (311)

Mixed quasi-étale surfaces and new surfaces of general type

open access: yes, 2012
In this thesis we define and study the mixed quasi-étale surfaces. In particularwe classify all the mixed quasi-étale surfaces whose minimal resolution of the singularities is a regular surface with p_g=0 and K^2>0.
Frapporti, Davide
core  

Minimum Zone Evaluation of the Form Errors of Quadric Surfaces

open access: yes, 2011
Quadric surfaces commonly exist in natural objects and artificial components. It is widely needed to evaluate the form quality of a measured data set, but the mostly used least squares method will lead to over-estimation and its results are not ...
Xiangchao Zhang   +6 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

A cone conjecture for log Calabi-Yau surfaces

open access: yesForum of Mathematics, Sigma
We consider log Calabi-Yau surfaces $(Y, D)$ with singular boundary. In each deformation type, there is a distinguished surface $(Y_e,D_e)$ such that the mixed Hodge structure on $H_2(Y \setminus D)$ is split.
Jennifer Li
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Nodal curves on surfaces of general type

open access: yesMathematische Annalen, 1997
We study the family of irreducible curves with $δ$ nodes belonging to a free linear system $|C|$ with smooth general member on a surface $S$ such that $|K_S|$ is ample. Under the assumption that $C$ is numerically equivalent to $pK_S$, $p\ge 3$ rational, we give an upper bound on $δ$ ensuring that the family is smooth of codimension $δ$ in $|C|$ (plus ...
CHIANTINI, LUCA, Sernesi E.
openaire   +3 more sources

General rotational surfaces in Euclidean space $\mathbb{E}^4$ with pointwise 1-type Gauss map

open access: yes, 2012
In this paper, we study general rotational surfaces in $\mathbb E^4$ with pointwise 1-type Gauss map. We consider general rotational surfaces in $\mathbb E^4$ whose meridian curves lie in two-dimensional planes. We firstly obtain all general rotational
Nurretin Cenk Turgay   +3 more
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

THE SIDE PANELS TOOTH CONTACT SURFACES CARIES GENDER DIFFERENCES INCIDENCE

open access: yesКубанский научный медицинский вестник, 2014
This article discusses the gender differences study results up to the frequency of occurrence of the most difficult diagnosed caries process located in the area between the contacts.
E. A. Bragin, A. V. Kheigetyan
doaj  

Constructions and moduli of surfaces of general type and related topics

open access: yes, 2023
In this thesis we treat two topics: the construction of minimal complex surfaces of general type with $p_g=q=2,3$ and an extension of Schur's concept of a representation group for projective representations to the setting of semi-projective ...
ALESSANDRO, MASSIMILIANO
core   +1 more source

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