Results 81 to 90 of about 316,671 (311)

GENERAL ROTATIONAL SURFACES WITH POINTWISE 1-TYPE GAUSS MAP IN PSEUDO-EUCLIDEAN SPACE E-2(4)

, 2015
WOS: 000352485200010In this paper, we study general rotational surfaces in the 4- dimensional pseudo-Euclidean space E-2(4) and obtain a characterization of flat general rotation surfaces with pointwise 1-type Gauss map in E-2(4) and give an example of ...
Yayli, Yusuf, Aksoyak, Ferdag Kahraman
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

On the geography of surfaces of general type with fixed fundamental group

, 2020
Tesis (Doctor en Matemática)--Pontificia Universidad Católica de Chile, 2020In this thesis, we study the geography of complex surfaces of general type with respect to the topological fundamental group.
Troncoso Igua, Sergio
core   +1 more source

The classification of minimal irregular surfaces of general type with K^2= 2p_g [PDF]

, 2014
According to a result of O. Debarre from 1982 minimal irregular surfaces of general type satisfy K2 ≥ 2p_g.
Ciliberto C., Mendes Lopes M., PARDINI, RITA   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Three-form periods on Calabi-Yau fourfolds: toric hypersurfaces and F-theory applications

Journal of High Energy Physics, 2017
The study of the geometry of Calabi-Yau fourfolds is relevant for compactifications of string theory, M-theory, and F-theory to various dimensions. This work introduces the mathematical machinery to derive the complete moduli dependence of the periods of
Sebastian Greiner, Thomas W. Grimm
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Comparative Analysis of the Nail and Screw Withdrawal Resistances of Fir (Abies Mill.), Cherry (Prunus Avium L.), Walnut (Juglans Regia L.) and Oak (Quercus L.) Wood

Düzce University Faculty of Forestry Journal of Forestry, 2006
In this study, the nail and screw withdrawal resistance (NWR and SWR) of wooden materials obtained from Fir (Abies Mill.), Cherry (Prunus avium L.), Walnut (Juglans regia L.) and Oak (Quercus L.) on the tangential, radial and transverse cut surfaces were
Murat Kılıç, Erol Burdurlu, İlker Usta, Umut Özgür Berker, Pelin Oduncu   +4 more
doaj  

Diffusion of Cd and Te adatoms on CdTe(111) surfaces: A computational study using density functional theory

AIP Advances, 2015
CdTe is one of the most promising semiconductor for thin-film based solar cells. Here we report a computational study of Cd and Te adatom diffusion on the CdTe (111) A-type (Cd terminated) and B-type (Te terminated) surfaces and their migration paths ...
Ebadollah Naderi, Sachin Nanavati, Chiranjib Majumder, S. V. Ghaisas   +3 more
doaj   +1 more source