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Surfactin Mitigates Dextran Sodium Sulfate-Induced Colitis and Behavioral Disorders in Mice by Mediating Gut-Brain-Axis Balance.

Journal of Agricultural and Food Chemistry, 2023
Ulcerative colitis (UC) is associated with brain neurotransmitter disorders and intestinal dysbiosis. Bacillus amyloliquefaciens fmb50 produces the lipopeptide surfactin, which has a wide range of biological activities.
Xiaoyu Chen   +5 more
semanticscholar   +1 more source

Synthesis of Aza-Surfactin and 3-Epi-Aza-Surfactin

HETEROCYCLES, 2012
Two synthetic approaches to aza surfactins are reported. In the first our recently developed synthesis of unnatural ß3 amino acids was used to prepare the requisite monomer which was used in solid phase peptide synthesis and followed by macrolactamization of a partially protected precursor. In the second the corresponding ß3 N hydroxyaminoacid was used
Jeffrey W. Bode   +3 more
openaire   +1 more source

Surfactin-Conjugated Silver Nanoparticles as an Antibacterial and Antibiofilm Agent against Pseudomonas aeruginosa.

ACS Applied Materials and Interfaces, 2023
The emergence of antimicrobial resistance is an alarming global health concern and has stimulated the development of novel functional nanomaterials to combat multi-drug-resistant (MDR) bacteria.
Lutfur Rahman   +12 more
semanticscholar   +1 more source

Interfacial properties of surfactin

Journal of Colloid and Interface Science, 1992
Abstract Surfactin is a lipopeptide produced by various strains of Bacillus subtilis and is a very powerful surfactant. Here we present the first report on the interfacial behavior of surfactin. The adsorption, Γmax, of surfactin at the interface of diluted solutions (5 × 10−8 to 5 × 10−7M) is around 3 × 1018 molecule m−2, a value indicating that ...
Régine Maget-Dana, Marius Ptak
openaire   +1 more source

Hydrolysis of surfactin over activated carbon

Bioorganic Chemistry, 2019
Surfactin is obtained through biocatalysis by microorganisms. In our biorefinery concept, it is purified on activated carbon (AC) during downstream processing. Besides cyclic surfactin, it is possible to obtain linear surfactin analogues, when AC with specific properties is used.
Hanna, Fałtynowicz   +4 more
openaire   +3 more sources

Surfactin-like lipopeptides from Bacillus clausii efficiently bind to spike glycoprotein of SARS-CoV-2

Journal of Biomolecular Structure and Dynamics, 2023
The coronavirus disease 2019 (COVID-19) rapidly spread across the globe, infecting millions and causing hundreds of deaths. It has been now around three years but still, it remained a serious threat worldwide, even after the availability of some vaccines.
Piyush Baindara   +4 more
semanticscholar   +1 more source

A new surfactin-C17 produced by Bacillus subtilis TD7 with a low critical micelle concentration and high biological activities

New Journal of Chemistry, 2023
A new member of the surfactin family of microbial lipopeptide has been isolated from the cell broth of Bacillus subtilis TD7 by a combination of organic solvent extraction and RP-HPLC,...
Wan-Qi Qin   +9 more
semanticscholar   +1 more source

Enhancing surfactin production in Bacillus subtilis: Insights from proteomic analysis of nitrate-induced overproduction and strategies for combinatorial metabolic engineering.

Bioresource Technology
Surfactin biosynthesis in Bacillus subtilis is intricately regulated by environmental conditions. In the present study, addition of nitrate, a nitrogen source, increased the production of surfactin in B.
Li Xia, Zhengjie Hou, Fuzhou Zhu, J. Wen
semanticscholar   +1 more source

Surfactin suppresses osteoclastogenesis via the NF-κB signaling pathway, promotes osteogenic differentiation in vitro, and inhibits oestrogen deficiency-induced bone loss in vivo.

International Immunopharmacology, 2023
BACKGROUND Fractures caused by osteoporosis (OP) are one of the main causes of death in the elderly, bringing a heavy burden to the country and society. The imbalance between osteoblast-mediated osteogenesis and osteoclast-mediated bone resorption is an ...
Zhihui Kuang   +10 more
semanticscholar   +1 more source

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