Results 71 to 80 of about 211,573 (276)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Requirement Analysis for an Aerial Relay in Emergency Response Missions

open access: yesCurrent Directions in Biomedical Engineering, 2020
First aid of patients at the scene of an emergency requires an adequate flow of information. The publicly funded research project MOMENTUM aims at seamlessly connecting the point of care to the hospital.
Gruner Jonas   +4 more
doaj   +1 more source

Robot Autonomy for Surgery

open access: yes, 2017
Autonomous surgery involves having surgical tasks performed by a robot operating under its own will, with partial or no human involvement. There are several important advantages of automation in surgery, which include increasing precision of care due to ...
Das, Nikhil, Yip, Michael
core   +1 more source

Autonomous Tissue Scanning under Free-Form Motion for Intraoperative Tissue Characterisation

open access: yes, 2020
In Minimally Invasive Surgery (MIS), tissue scanning with imaging probes is required for subsurface visualisation to characterise the state of the tissue. However, scanning of large tissue surfaces in the presence of deformation is a challenging task for
Cartucho, Joao   +2 more
core   +1 more source

Biomechanics for computer-assisted surgery [PDF]

open access: yesComputer Methods in Biomechanics and Biomedical Engineering, 2012
TIMC-IMAG Laboratory (http://www-timc.imag.fr) is a 250-people laboratory devoted to translational and fundamental research at the intersection between medicine, information science and technology ...
openaire   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Computer Assisted Orthopaedic Surgery – CAOS

open access: yesBosnian Journal of Basic Medical Sciences, 2006
The use of computer navigation in orthopedic surgery allows for real time intraoperative feedback resulting in higher precision of bone cuts, better alignment of implants and extremities, easier fracture reductions, less radiation and better documentation than what is possible in classical orthopaedic procedures.
Enes M, Kanlić   +2 more
openaire   +3 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Comparison of spectral characteristics in human and pig biliary system with hyperspectral imaging (HSI)

open access: yesCurrent Directions in Biomedical Engineering, 2020
Injuries to the biliary tree during surgical, endoscopic or invasive radiological diagnostic or therapeutic procedures involving the pancreas, liver or organs of the upper gastrointestinal tract give rise to the need to develop a method for clear ...
Cooney Gary Sean   +5 more
doaj   +1 more source

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