Results 111 to 120 of about 641,771 (314)

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Submandibular Gland Invasion From a Metastatic Lymph Node in Patients With Buccal Mucosal Squamous Cell Carcinoma: A Case Report

Case Reports in Dentistry
This report presents a rare case of direct invasion from a metastatic submandibular lymph node (SMLN) to submandibular gland (SMG) in a resected specimen of neck dissection (ND) of buccal mucosal squamous cell carcinoma (SCC).
Moeka Bukawa, Kenji Yamagata, Satoshi Fukuzawa, Shohei Takaoka, Fumihiko Uchida, Naomi Ishibashi-Kanno, Hiroki Bukawa   +6 more
doaj   +1 more source

The Codos : year book of the College of Dental and Oral Surgery of New York /

The College of Dental and Oral Surgery of New York, founded in 1892 as the New York Dental School, merged in 1923 with the Columbia University School of Dentistry to become the University's School of Dental and Oral Surgery.
Columbia University. College of Dental Medicine., Columbia University. School of Dental and Oral Surgery., College of Dental and Oral Surgery of New York.   +2 more
core  

Assessment of pre and postoperative anxiety in patients undergoing ambulatory oral surgery in primary care

, 2017
Background To analyze the pre- and postoperative anxiety level in patients undergoing ambulatory oral surgery (AOS) in a primary healthcare center (PHC).
Luque Romero, Luis Gabriel, Reyes Gilabert, Eva, Bejarano Ávila, Gracia, Rollón Mayordomo, Ángel, Garcia Palma, Alfonso, Infante Cossío, Pedro Antonio   +5 more
core   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Spontaneous Exposure of Mandibular Torus: A Case Report and Surgical Management

Case Reports in Dentistry
Conclusion: The patient recovered without complications, and no recurrence of symptoms was noted during the 1-year follow-up. This case highlights the need for prompt surgical intervention in cases of spontaneous torus exposure and the importance of ...
Priscilla Sergi, Subhi Tayeb, Carlo Barausse, Gerardo Pellegrino, Lorenzo Roccoli, Stefano Ratti, Pietro Felice   +6 more
doaj   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

A French practice study within the Group for the Study of Oral Mucosa (GEMUB): Allopathic treatment of oral lichen

Journal of Oral Medicine and Oral Surgery
Lichen planus is a chronic inflammatory dermatosis of unknown origin, generally affecting the skin, nails and scalp. It can also affect the mucous membranes of the oral cavity and ano-genital region. Due to the paucity of randomised controlled trials, no
Ménager Lélia, Galvez Paul, Catros Sylvain, Fénélon Mathilde, Fricain Jean-Christophe   +4 more
doaj   +1 more source

Morbidity of salvage surgery for recurrent oral/oropharyngeal cancers after radiotherapy or chemoradiation

, 2015
BACKGROUND: Oral/oropharyngeal cancer is the eighth most common malignancy worldwide and persists as a serious problem in many regions of the world. With the multidisciplinary treatment of oral/oropharyngeal cancers, the survival rate is increasing in ...
Zheng, GS, Su, Y, Liao, GQ, Liang, YJ
core   +1 more source

Psychological Functioning of Patients Undergoing Oral Surgery Procedures during the Regime Related with SARS-CoV-2 Pandemic

, 2020
The coronavirus pandemic has become a huge global challenge medically, economically and psychologically. The COVID-19 pandemic shows that the population can experience general psychological distress.
Dorota Pylińska-Dąbrowska, Wiesław Jerzy Cubała, Barbara Alicja Jereczek-Fossa, Daniela Alterio, Anna Starzyńska, Karolina Ragin   +5 more
core   +1 more source