Results 171 to 180 of about 1,023,614 (265)

Histological Findings in Testes of Baboons (Papio spp.) and Dwarf Bucks (Capra hircus) Subject to Repeated Immunisation Against GnRH

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Long‐term repeated immunisation against GnRH resulted in the absence of active spermatogenesis and may lead to irreversible infertility in dwarf bucks and baboons. Histological examination revealed a marked reduction of the seminiferous tubular lumen, complete depletion of germ cells, germ cell vacuolization and tubular hyalinization.
Teresa Ferrín   +8 more
wiley   +1 more source

Evaluation of triplet therapy combined with robot‐assisted cytoreductive prostatectomy for high‐volume metastatic prostate cancer: a multicentre randomised controlled trial protocol

open access: yesBJU International, Volume 138, Issue 5, Page 807-814, November 2026.
Background Prostate cancer (PCa) is the second most common cancer in men. For patients with high‐volume metastatic PCa (mPCa) who are fit for docetaxel, a triplet therapy regimen consisting of androgen deprivation therapy (ADT), chemotherapy, and an androgen receptor pathway inhibitor (ARPI) is recommended.
Xiangwei Yang   +7 more
wiley   +1 more source

Erratum: Aluwé, M. et al. Exploratory Survey on European Consumer and Stakeholder Attitudes towards Alternatives for Surgical Castration of Piglets. Animals 2020, 10, 1758. [PDF]

open access: yesAnimals (Basel), 2020
Aluwé M   +22 more
europepmc   +1 more source

A retrospective analysis of bacterial pathogens in wounds in an equine hospital (2017–2022)

open access: yesEquine Veterinary Education, Volume 38, Issue 11, Page e910-e918, November 2026.
Summary Background Bacterial infections are a major cause of morbidity in horses, particularly in soft tissue wounds (STW) and surgical site infections (SSI). Rising antimicrobial resistance poses challenges for timely treatment. Knowledge of common pathogens and their resistance patterns is therefore essential.
J. Nebes   +3 more
wiley   +1 more source

Towards the Abandonment of Surgical Castration in Pigs: How is Immunocastration Perceived by Italian Consumers? [PDF]

open access: yesAnimals (Basel), 2019
Di Pasquale J   +7 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, Volume 600, Issue 19, Page 2850-2873, October 2026.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, Volume 20, Issue 10, Page 2424-2448, October 2026.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

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