Results 171 to 180 of about 1,023,614 (265)
Long‐term repeated immunisation against GnRH resulted in the absence of active spermatogenesis and may lead to irreversible infertility in dwarf bucks and baboons. Histological examination revealed a marked reduction of the seminiferous tubular lumen, complete depletion of germ cells, germ cell vacuolization and tubular hyalinization.
Teresa Ferrín +8 more
wiley +1 more source
Background Prostate cancer (PCa) is the second most common cancer in men. For patients with high‐volume metastatic PCa (mPCa) who are fit for docetaxel, a triplet therapy regimen consisting of androgen deprivation therapy (ADT), chemotherapy, and an androgen receptor pathway inhibitor (ARPI) is recommended.
Xiangwei Yang +7 more
wiley +1 more source
Erratum: Aluwé, M. et al. Exploratory Survey on European Consumer and Stakeholder Attitudes towards Alternatives for Surgical Castration of Piglets. Animals 2020, 10, 1758. [PDF]
Aluwé M +22 more
europepmc +1 more source
A retrospective analysis of bacterial pathogens in wounds in an equine hospital (2017–2022)
Summary Background Bacterial infections are a major cause of morbidity in horses, particularly in soft tissue wounds (STW) and surgical site infections (SSI). Rising antimicrobial resistance poses challenges for timely treatment. Knowledge of common pathogens and their resistance patterns is therefore essential.
J. Nebes +3 more
wiley +1 more source
Towards the Abandonment of Surgical Castration in Pigs: How is Immunocastration Perceived by Italian Consumers? [PDF]
Di Pasquale J +7 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The application of polypropylene mesh for testicular prosthesis in surgical castration for patients with prostate cancer. [PDF]
Xia YH +7 more
europepmc +1 more source
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen +19 more
wiley +1 more source
Surgical or irradiation castration for patients with advanced breast cancer [PDF]
openaire +2 more sources

