Results 101 to 110 of about 9,068,321 (297)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Enhancing surgical internship preparedness through a Transition to Internship Bootcamp

Purpose This study aims to assess the effectiveness of a 4th-year medical student (MS4) Transition to Internship Bootcamp curriculum in improving students’ attitudes towards and perception of preparedness for surgical residency.
Hui, Vanessa W., Delamater, Jessica M., Collie, Brianna L., Huerta, Carlos T., Hernandez, Alexandra, Sands, Ryan H., Sands, Laurence R., Goel, Neha, Joshi, Priyashma   +8 more
core   +1 more source

Identification of Warning Signs During Selection of Surgical Trainees

, 2019
Objective: The aim was to document empirical observations about antecedents to and practices of unsuitable behaviours amongst surgical trainees and develop an interview guide that could be used for the selection process.
Mathieu, Chris,, Hagelsteen, Kristine,, Bergenfelz, Anders,, Lund University., Johansson, Britt Marie,   +4 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Mapping surgical deserts of cardiovascular training in Latin America: A geospatial and structural analysisCentral MessagePerspective

JTCVS Open
Objective: Latin America faces significant disparities in cardiovascular surgery training access. We used a driven geospatial analysis to map surgical deserts—underserved regions to surgical education—and quantified disparities through population ...
Wildor Samir Cubas, MD, MSc, Joaquín Gundelach, MD, Lorena Montes, MD, Maximiliano Hernández, MD, Santiago Cubas, MD, Carolina Sosa Vota, MD, Juan Andrés Montero, MD, Gerardo Soca, MD, MSc, Víctor Dayan, MD, PhD, Michael W.A. Chu, MD, MEd   +9 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Attending Surgeons’ Perspectives on Promoting Flourishing During Residency

International Medical Education
Through semi-structured interviews with attending surgeons, this exploratory qualitative study examined ways in which eleven surgeons create conditions for residents to flourish in the clinical learning environment.
Randi Stanulis, Luke Beauchamp, John Pestenariu, Scot Stanulis, Linda Qu, Rachel Gerth, Alicia Knickerbocker, Jordan Knepper   +7 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Mohs Surgical Reconstruction Educational Activity: a resident education tool

, 2017
Julie A Croley,1 C Helen Malone,1 Brandon P Goodwin,1 Linda G Phillips,2 Eric L Cole,2 Richard F Wagner1 1Department of Dermatology, 2Division of Plastic Surgery, Department of Surgery, The University of Texas Medical Branch, Galveston, TX, USA ...
Croley JA, Wagner RF, Malone CH, Goodwin BP, Cole EL, Phillips LG   +5 more
core