Results 51 to 60 of about 9,068,321 (297)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Current Trend of Accreditation within Medical Education [PDF]

, 2020
Currently, accreditation within medical education is a priority on the agenda for many countries worldwide. The World Federation for Medical Education’s (WFME) launch of its first trilogy of standards in 2003 was a seminal event in promoting ...
Korean Medical Education Review (의학교육논단)
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Hospice and Palliative Care Education for Medical Students in Korea [PDF]

, 2020
Hospice and palliative care (HPC) education is an essential component of undergraduate medical education. Since February 4th, 2018, withholding and withdrawing life-sustaining treatment at the end of life (EOL) has been permitted in Korea as put forth by
Korean Medical Education Review (의학교육논단)
core   +1 more source

Continuous intraoperative neuromonitoring for thyroid cancer surgery: A prospective study

Laryngoscope Investigative Otolaryngology, 2019
Objective We evaluated the utility of continuous intraoperative neuromonitoring (CIONM) during surgery for thyroid cancer (TC) in an educational university hospital. Study Design Prospective observational study.
Naoyoshi Onoda, Satoru Noda, Yukie Tauchi, Yuka Asano, Yukina Kusunoki, Sae Ishihara, Tamami Morisaki, Shinichiro Kashiwagi, Tsutomu Takashima, Masaichi Ohira   +9 more
doaj   +1 more source

Genitourinary Reconstructive Surgery Curriculum and Postgraduate Training Program Development in the Caribbean

Société Internationale d’Urologie Journal, 2021
ObjectivesTo describe the development of a genitourinary reconstructive fellowship curriculum and the establishment of the first genitourinary reconstructive and pelvic floor postgraduate training program in the Caribbean ...
Jessica DeLong, Ramon Virasoro
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Effectiveness of an In-Service Education Program to Improve Patient Safety Directed at Surgical Residents : A Randomized Controlled Trial

, 2019
Background: Patient safety is a critical issue in healthcare services particularly in surgical units and operation rooms because of the high prevalence and risk of medical errors in such settings.
Koenig, Harold G.,, Saffari, Mohsen,, O'Garo, Keisha-Gaye N.,, Ameryoun, Ahmad,, Pakpour, Amir H.,, Nikoobakht, Mehdi,, Yaseri, Mahdi,   +6 more
core   +1 more source

Application of Social Constructivism in Medical Education [PDF]

, 2020
The purpose of this study is to discuss the main principles and concepts of social constructivism, examine the literature on the application of social constructivism in medical education, and explore the meaning and limitations of the utilization of ...
Korean Medical Education Review (의학교육논단)
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source