Results 111 to 120 of about 15,686,169 (410)

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Conservative surgical treatment in cervical dysplastic lesions associated with cystorectocele [PDF]

, 2019
The treatment of cervical intraepithelial neoplasia aims at removing the squamocolumnar junction area, including abnormal tissues, up to the healthy tissue.
Braila, Anca D, Braila, Mihai, Deca, Mihai, Lungulescu, Cristian, Obleaga, Cosmin V, Puca, Bogdan Marian, Saad, Hany   +6 more
core   +2 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Recent advances in surgical treatment of hepatocellular carcinoma.

Drug Discoveries & Therapeutics, 2015
Hepatocellular carcinoma (HCC) is a common and lethal malignancy worldwide that arises within the context of a host of diseases. Surgery is the primary option for tumor treatment and is thus the most effective therapy to allow the best overall survival ...
T. Song
semanticscholar   +1 more source

A Retrospective Surgical Experience Regarding Open and Laparoscopic Procedures of the Hepatic Hydatid Cyst with an up to Date Complete Review of the Literature And a Focus On Original Romanian Techniques [PDF]

, 2016
Introduction: Even though the development of the recent anti-parasitic drugs has led to a high degree of efficiency, surgical treatment still remains the gold standard for a number of conditions. Material and method.
Moldovan, Cosmin Alec, Moldovan, Diana, Ungureanu, Dan Florin, Ungurianu, Laurentiu   +3 more
core   +3 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

The Surgical Treatment of Ascites [PDF]

the american journal of the medical sciences, 1914
n ...
White, J. William, Thomas, T. Turner
openaire   +3 more sources

Clinicopathological Profile and Surgical Treatment of Abdominal Tuberculosis: A Single Centre Experience in Northwestern Tanzania. [PDF]

, 2013
Abdominal tuberculosis continues to be a major public health problem worldwide and poses diagnostic and therapeutic challenges to general surgeons practicing in resource-limited countries.
A Singhal, A Soylu, A Zafar, AU Arif, B Anuradha, BM Mawalla, C Bolukbas, E Akgun, EF Lyamuya, EHG Ahmed, FF Paustian, G Engin, H Ming-Luen, HS Shukla, HS Wang, Hyasinta Jaka, IA Khan, JE Gomez, JF Sharp, Joseph B Mabula, K Lonnroth, K Niaz, K-K Tan, KM Gondal, KR Palmer, L Werbeloff, M Akbar, M Saaiq, M Urassa, Mabula D Mchembe, Ministry of Health and Social Welfare, MJ Rajpoot, MP Sharma, MR Khan, MS Shaikh, MS Skopin, N Ali, N Wadhwa, NA Baloch, NV Addison, Peter F Rambau, Phillipo L Chalya, PJ Dolin, PJ Gupta, PJ Gupta, R Khan, RS Nyman, S Chandir, S Suri, SH Gondal, SM Khan, SP Misra, Stephen E Mshana, T Butt, T Iqbal, VK Kapoor, VK Kapoor, WP Homan   +57 more
core   +1 more source