Results 61 to 70 of about 621,364 (392)

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Low-cost wound protector for laparoscopic surgeries [PDF]

Revista do Colégio Brasileiro de Cirurgiões
The role of wound protectors in laparoscopic surgeries is highly controversial in the literature. Some studies demonstrate their benefit in reducing the rate of surgical site infections; however, these results are not reproducible across all procedures ...
CARLOS AUGUSTO METIDIERI MENEGOZZO, CRISTIANE PRESTES DA ROSA OLIVEIRA, ROBERTO RASSLAN, FELIPE KFOURI, ALBERTO BITRAN, RENATO SILVEIRA LEAL, SERGIO HENRIQUE BASTOS DAMOUS, EDIVALDO MASSAZO UTIYAMA   +7 more
doaj   +1 more source

Risk factors for wound infection in surgery for spinal metastasis [PDF]

, 2015
Wound infection rates are generally higher in patients undergoing surgery for spinal metastasis. Risk factors of wound infection in these patients are poorly understood.
A Grzegorzewska, AF Pull ter Gunne, D. van Popta, H Majeed, H Pascal-Moussellard, I McPhee, I. Siddique, IA Omeis, J Wise, J. Stephenson, KA Greene, N Sarhill, R. R. Verma, R. Rodrigues-Pinto, S Boriani, S Demura, S Dickhaut, S. Kumar, S. Mohammad   +18 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Role of single-ring oval disposable wound protecting device in preventing surgical site infection in laparoscopic colorectal resections

Journal of Minimal Access Surgery
Context: Surgical site infections (SSI) continue to be a major cause of morbidity, mortality, prolonged hospital stays and a major reason of financial burden to health-care providers and patients after major abdominal surgeries.
Prakash Kurumboor, Sidharth Chacko, I S Vipin, Rohan Prakash, Ashna S Pal   +4 more
doaj   +1 more source

Nonpharmacological Prevention of Surgical Wound Infections [PDF]

Clinical Infectious Diseases, 2002
Postoperative wound infection is a common and serious complication of surgery. This review will focus on 2 factors known to modulate perioperative immunity: maintenance of perioperative normothermia and provision of supplemental perioperative oxygen. Hypothermia causes numerous adverse outcomes, including morbid myocardial events, increased blood loss ...
Daniel I. Sessler, Ozan Akca
openaire   +3 more sources

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

A nonsurgical protocol for management of postarthroplasty wound drainage

Arthroplasty Today, 2018
Persistent wound drainage after total joint arthroplasty can potentiate periprosthetic joint infection. Although current recommendations are to treat persistent wound drainage with surgical debridement, we believe nonoperative treatment may be successful
Michael S. Reich, MD, Kace A. Ezzet, MD
doaj   +1 more source

Surgical wound infection [PDF]

, 1999
Objective. To review the risk factors for surgical would infection; the use of prophylactic antibiotics in the prevention of wound infection; and the benefits of wound surveillance programmes to reduce the rate of surgical wound infection.
Chan, SC, Mak, KC, Nandi, PL, So, YP, Soundara Rajan, S   +4 more
core  

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source