Results 51 to 60 of about 133,335 (273)
Surrogate-assisted management of water-flooding, as a reservoir production optimization strategy, dynamically adjusts development schemes at each production step, leading to improved economic benefits and enhanced recovery.
Lian Wang +9 more
doaj +1 more source
Meta-heuristic algorithms are widely used in complex problems that cannot be solved by traditional computing methods due to their powerful optimization capabilities. However, for high-complexity problems, the fitness function evaluation may take hours or
Jeng-Shyang Pan +4 more
doaj +1 more source
Quantile-based optimization under uncertainties using adaptive Kriging surrogate models [PDF]
Uncertainties are inherent to real-world systems. Taking them into account is crucial in industrial design problems and this might be achieved through reliability-based design optimization (RBDO) techniques.
Bourinet, J. -M. +3 more
core +3 more sources
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Data-efficient Neuroevolution with Kernel-Based Surrogate Models [PDF]
Surrogate-assistance approaches have long been used in computationally expensive domains to improve the data-efficiency of optimization algorithms. Neuroevolution, however, has so far resisted the application of these techniques because it requires the ...
Lehman J +4 more
core +3 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Surrogate based blended-wing-body underwater glider shape optimization design
In order to improve the design quality and optimization efficiency for blended-wing-body underwater glider(BWBUG) shape design optimization problems, a surrogate-based blended-wing-body underwater glider shape optimization(SBUGSO) framework is proposed ...
doaj +1 more source
Parallel surrogate-assisted global optimization with expensive functions – a survey [PDF]
Surrogate assisted global optimization is gaining popularity. Similarly, modern advances in computing power increasingly rely on parallelization rather than faster processors.
Chaudhuri, Anirban +2 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Space mapping (SM) methodology has been recognized as a powerful tool for accelerating electromagnetic (EM)-based yield optimization. This paper proposes a novel parallel space-mapping based yield-driven EM optimization technique incorporating trust ...
Jianan Zhang +4 more
doaj +1 more source

