Results 51 to 60 of about 64,315 (262)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Superstatistical fluctuations in time series: Applications to share-price dynamics and turbulence

, 2009
We report a general technique to study a given experimental time series with superstatistics. Crucial for the applicability of the superstatistics concept is the existence of a parameter $\beta$ that fluctuates on a large time scale as compared to the ...
A. Erdélyi, Christian Beck, Erik Van der Straeten, J.-P. Bouchard, S. M. Duarte Queirós, S. M. Ross   +5 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

On a novel approach for optimizing composite materials panel using surrogate models [PDF]

, 2011
This paper describes an optimization procedure to design thermoplastic composite panels under axial compressive load conditions. Minimum weight is the goal. The panel design is subject to buckling constraints.
Akcay-Perdahcioglu, D., Boer, A. de, De Guido, S., Geijselaers, H.J.M.   +3 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

The Optimal Uncertainty Algorithm in the Mystic Framework [PDF]

, 2012
We have recently proposed a rigorous framework for Uncertainty Quantification (UQ) in which UQ objectives and assumption/information set are brought into the forefront, providing a framework for the communication and comparison of UQ results.
McKerns, M., Ortiz, M., Owhadi, H., Scovel, C., Sullivan, T. J.   +4 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Simultaneous OPEX and carbon footprint reduction with hydrogen enhancement in autothermal reforming: a machine learning–based surrogate modeling and optimization framework

Results in Engineering
The constrained optimization of autothermal reforming (ATR) processes involving multiple conflicting objectives, such as operational expenditure (OPEX), carbon footprint, and hydrogen production, remains a critical challenge in process systems ...
Sahar Shahriari, Davood Iranshahi
doaj   +1 more source

Design Optimization Utilizing Dynamic Substructuring and Artificial Intelligence Techniques [PDF]

, 2008
In mechanical and structural systems, resonance may cause large strains and stresses which can lead to the failure of the system. Since it is often not possible to change the frequency content of the external load excitation, the phenomenon can only be ...
Akcay Perdahcioglu, D., Boer, A. de, Ellenbroek, M.H.M., Hoogt, P.J.M. van der   +3 more
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source