Results 171 to 180 of about 557,108 (293)

MULTI-OBJECTIVE OPTIMIZATION DESIGN OF MOTOR TRAIN UNIT TRUCK FRAME BASED ON HYBRID ADDITION KRIGING SURROGATE MODEL

Jixie qiangdu
To enhance the computational efficiency of structural lightweight design for complex structures, a structural lightweight design method based on the Kriging surrogate model is proposed.
WANG Weiqi, SONG Yubo, WANG Ying
doaj  

Rapid thickness distribution prediction of superplastic formed parts based on geometry adapted PSO-BP neural network surrogate model. [PDF]

Sci Rep
Sun M, Xiong C, Zhou Y, Zhang X, Yuan A, Sun Y, Li Y.   +6 more
europepmc   +1 more source

A generalised deep learning-based surrogate model for homogenisation utilising material property encoding and physics-based bounds. [PDF]

Sci Rep, 2023
Nakka R, Harursampath D, Ponnusami SA.
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Aspirin inhibition and recovery of cyclooxygenase activity and thromboxane biosynthesis in human megakaryocytes: a translational surrogate model. [PDF]

J Pharmacol Exp Ther
Mallah ZI, Petrucci G, Ayoub AJ, Farhoud MA, Jelwan JG, Lucchisani S, Fakih AK, Badran B, Hamade E, Patrono C, Rocca B, Habib A.   +11 more
europepmc   +1 more source

Tendon Stress Estimation from Strain Data of a Bridge Girder Using Machine Learning-Based Surrogate Model. [PDF]

Sensors (Basel), 2023
Khayam SU, Ajmal A, Park J, Kim IH, Park JW.   +4 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Multi-Epitope DNA-Based Feline Immunodeficiency Virus Vaccine Construct Designed by Immunoinformatic and Machine Learning Tools as a Surrogate Model for HIV Vaccine Development. [PDF]

Pathogens
Michalka T, Shah AU, Liang T, Hemida MG.
europepmc   +1 more source

Surrogate-Model-Based Interval Analysis of Spherical Conformal Array Antenna with Power Pattern Tolerance. [PDF]

Sensors (Basel), 2022
Ding G, Li P, Rocca P, Chang J, Xu W.
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source