Results 71 to 80 of about 247,811 (265)
IEEE AccessExpensive optimization problems are characterized by the significant amount of time and resources needed to determine the quality of potential solutions.
Mario Garza-Fabre +3 more
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
AI-Driven Surrogate Model for Room Ventilation
FluidsThe control of ventilation systems is often performed by automatic algorithms which often do not consider the future evolution of the system in its control politics. Digital twins allow system forecasting for a more sophisticated control.
Jaume Luis-Gómez +7 more
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Decomposition-Assisted Computational Technique Based on Surrogate Modeling for Real-Time Simulations
Complexity, 2017 The development of complex simulation systems is extremely costly as it requires high computational capability and expensive hardware. As cost is one of the main issues in developing simulation components, achieving real-time simulation is challenging ...
Nariman Fouladinejad +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Online learning supported surrogate-based flowsheet model maintenance
Digital Chemical EngineeringSurrogate-based flowsheet model calibration is a critical extension of using flowsheet models in Digital Twin (DT) systems. However, maintaining accurate surrogates over time is increasingly challenging, especially when models are deployed in real-time ...
Balázs Palotai +3 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Journal of Petroleum Exploration and Production TechnologySurrogate-assisted management of water-flooding, as a reservoir production optimization strategy, dynamically adjusts development schemes at each production step, leading to improved economic benefits and enhanced recovery.
Lian Wang +9 more
doaj +1 more source
Surrogate Model Assisted Design of CSRR Structure using Genetic Algorithm for Microstrip Antenna Application [PDF]
Radioengineering, 2020 Soft-computational approaches have enabled quicker and more efficient means for antenna design. In the present work, a genetic algorithm (GA) based method is reported for the design of complementary split ring resonator (CSRR) structures for antenna ...
K. Sarmah, S. Goswami, S. Baruah
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