Results 141 to 150 of about 22,195,649 (288)

Uncertainty propagation in pore water chemical composition calculation using surrogate models. [PDF]

Sci Rep, 2022
Sochala P, Chiaberge C, Claret F, Tournassat C.   +3 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Research on Surrogate Model of Dam Structural Behavior for Multi‐Output Problem

Engineering Reports
The establishment efficiency of the surrogate model is often affected by the multi‐output problem during the establishment process. It is an urgent issue to solve how to establish a multi‐output joint surrogate model more quickly while ensuring a certain
Yuan Qiao, Liang Jiaming, Li Zhanchao, Ebrahim Yahya Khailah   +3 more
doaj   +1 more source

Adaptive Weighted Strategy Based Integrated Surrogate Models for Multiobjective Evolutionary Algorithm. [PDF]

Comput Intell Neurosci, 2022
Bao K, Fang W, Ding Y.
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Multi-objective robust optimization using adaptive surrogate models for problems with mixed continuous-categorical parameters. [PDF]

Struct Multidiscipl Optim, 2022
Moustapha M, Galimshina A, Habert G, Sudret B.   +3 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Smart Thermostat Development and Validation on an Environmental Chamber Using Surrogate Modelling

Energies
The significant contribution of buildings to the global primary energy consumption necessitates the application of energy management methodologies at a building scale.
Leonidas Zouloumis, Nikolaos Ploskas, Nikolaos Taousanidis, Giorgos Panaras   +3 more
doaj   +1 more source

Efficient Ventricular Parameter Estimation Using AI-Surrogate Models. [PDF]

Front Physiol, 2021
Maso Talou GD, Babarenda Gamage TP, Nash MP.   +2 more
europepmc   +1 more source