Results 61 to 70 of about 167,709 (298)

Stress Relief and Support for Stability of Deep Mining Roadway with Thick Top Coal in Hujiahe Coal Mine with the Risk of Rock Burst

open access: yesShock and Vibration, 2021
Rock burst is a typical dynamic disaster in deep underground coal mining. Based on the support problems of the deep roadways in fully mechanized caving face 401111 of Hujiahe Coal Mine suffering from rock burst in Shaanxi Province of China, the failure ...
Wenjing Liu   +6 more
doaj   +1 more source

Study on the Convergence of Surrounding Rock in Shallow Buried Unsymmetrical Pressure Tunnel Construction

open access: yesJournal of Physics: Conference Series, 2023
Abstract In order to study the evolution law of tunnel convergence deformation during the construction of shallow buried unsymmetrical pressure tunnel, the deformation characteristics and evolution law of shallow buried unsymmetrical pressure tunnel during the three-step construction method are studied based on the background of Qingshui
Yu Hu   +5 more
openaire   +1 more source

Stability Analysis of Surrounding Rock in Circular Tunnels Based on Critical Support Pressure [PDF]

open access: yesAdvances in Civil Engineering, 2020
Accurate calculation for the critical support pressure of tunnels plays an important role in tunnel stability evaluation and support design. In this study, a mechanical model for circular tunnels is developed. Considering the intermediate principal stress and strain‐softening characteristic of rock mass, the critical support pressure when the plastic ...
Hao Fan, Lianguo Wang, Kai Wang
openaire   +2 more sources

Investigation of the evolution and control of fractures in surrounding rock under different pressure relief and support measures in mine roadways prone to rockburst events

open access: yesRoyal Society Open Science, 2021
This paper studies the evolution and control of surrounding rock under different pressure relief support conditions in mine roadways in which rockburst events have occurred.
Yongliang He   +3 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Experiment Study on Mechanical Evolution Characteristics of Coal and Rock under Three-Dimensional Triaxial Stress

open access: yesApplied Sciences, 2022
The surrounding rock is in a complex stress environment and its mechanical behavior is also complex, especially after the excavation of the coal seam, the phenomenon of stress release of surrounding rock often occurs.
Yabin Tao   +4 more
doaj   +1 more source

On-site Monitoring and Comparative Analysis about Surrounding Rock Pressure Variation with Time in Unsymmetrial Loading Tunnel

open access: yesIOP Conference Series: Earth and Environment, 2019
Bias Tunnes are common seen and it has complicated variation on their surrounding rock pressure. It is crucial for the security and stability of a tunnel to determine the variation law of surrounding rock pressure and on-site monitoring technology.
J. Hu   +4 more
semanticscholar   +1 more source

Enhancing mechanical characteristics of soft rock tunnel surrounding rock through radial yield pressure system [PDF]

open access: yes
This study investigated the efficacy of radial yield support as an active measure to mitigate stress and deformation in deep soft rock tunnels experiencing large deformation.
Xuhao ZHANG   +7 more
core   +1 more source

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