Results 71 to 80 of about 1,413,891 (297)

Seeing Surveillance: Twenty Years of Surveillance & Society

, 2022
This paper reflects on the development of surveillance studies over the twenty years since the first publication of Surveillance & Society. It starts by pointing to key contextual changes that have provided fertile ground for surveillance-focused ...
Fussey, Pete
core   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Clostridioides difficile clinical diagnostic test methods and results are associated with recovery of C. difficile by stool culture

Microbiology Spectrum
Accurate molecular epidemiology relies on recovering Clostridioides difficile from clinical specimens and is essential for informing public health responses, characterizing strains that cause disease, and tracking strain prevalence.
Andrew M. Skinner, Alice Y. Guh, Laurica A. Petrella, Susan Sambol, Adam Cheknis, Stuart Johnson, Christopher A. Czaja, Helen Johnston, Elizabeth Basiliere, Robin A. Dhonau, Lauren Korhonen, Ashley L. Paulick, Matthew H. Samore, Michelle Adamczyk, Amy S. Gargis, Dale N. Gerding   +15 more
doaj   +1 more source

Routine surveillance for the identification of drug resistant Tuberculosis in Tanzania: A cross-sectional study of stakeholders' perceptions.

PLoS ONE, 2019
BackgroundRoutine surveillance is required to monitor the performance of tuberculosis diagnostic programme and is essential for the rapid detection of drug resistance.
Basra Esmail Doulla, Stephen Bertel Squire, Eleanor MacPherson, Esther Stanslaus Ngadaya, Beatrice Kemilembe Mutayoba, Ivor Langley   +5 more
doaj   +1 more source

Weekly Influenza Surveillance Report Week 40 2002

, 2002
Welcome to the first influenza surveillance report of the 2002/2003 influenza season. This is the third year of influenza surveillance using computerised sentinel general practices in Ireland. The National Disease Surveillance Centre (NDSC) is working in
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core  

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Weekly Influenza Surveillance Report Week 40

, 2001
This is the first weekly influenza surveillance report of the 2001/2002 influenza season. This report is produced by the National Disease Surveillance Centre, in collaboration with the Virus Reference Laboratory, the Irish College of General ...
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core  

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

Weekly Influenza Surveillance Report Week 1 2004

, 2004
GP consultation rates for influenza-like illness (ILI) in Ireland increased slightly during week 1, this may be partly due to the disruption in reporting during the Christmas and New Year period.
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core