Results 191 to 200 of about 4,921,450 (294)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Implementation and Evaluation of a Social Networking Service-Based Mobile Patient-Generated Health Data System With Direct Electronic Medical Record Integration: Prospective Observational Study. [PDF]

JMIR Med Inform
Choi E, Lee S, Jeon J, Kim EJ.
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Author Correction: Database of surface water diversion sites and daily withdrawals for the Upper Colorado River Basin, 1980–2022

Scientific Data
Samuel F. Lopez, Jacob E. Knight, Fred D. Tilman, Melissa D. Masbruch, Daniel R. Wise, Casey J. Jones, Matthew P. Miller   +6 more
doaj   +1 more source

Exploring staff and students' understanding and experience of Public and Patient Involvement (PPI) in an Irish University. [PDF]

Res Involv Engagem
Kavanagh B, Grealis S, Haslett D, Kearney PM, Masterson L, Skeffington S, Racine E, Kelleher C.   +7 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Symptom burden, care pathways and treatment experiences of healthcare workers with post-COVID-19 syndrome (SCOPE-CARE): a mixed-methods study protocol. [PDF]

BMJ Open
Baumgart M, Luedtke L, Petter J, Kriston L, Nienhaus A, Härter M.   +5 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Pilot mHealth Text Messaging Program Targeting Parents During the First 2000 Days: Nonrandomized Repeat Cross-Sectional Analysis to Evaluate Feasibility, Engagement, Acceptability, and Potential Effectiveness. [PDF]

JMIR Mhealth Uhealth
Jackson J, Hudson N, Delaney T, Brown AL, Kavalec S, Pinfold J, Sewter R, McCormick H, Liackman R, Lecathelinais C, Davies L, Wolfenden L, Groombridge D, Tully B, Redman S, Smart T, Ghafournia N, Craven PD, Sutherland R, Sutherland R.   +19 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source