Results 211 to 220 of about 4,921,450 (294)

Tectonic Characteristics of the Juyanhai Depression in the Yingen-Ejinaqi Basin, Inner Mongolia, China, Based on Gravity, Electrical, and Seismic Data

ACS Omega
Haihong Xu, Junlin Zhou, Xiaofeng Han, Yuhong Li, Jianshe Wei, Bo Song, Jizhong Shi, Wei Xu, Chunguan Zhang, Baowen Wang, Fei Zhao   +10 more
doaj   +1 more source

The Construction and Evaluation of a Pediatric Emergency Medicine Bootcamp for Graduating Emergency Medicine Residents. [PDF]

AEM Educ Train
Hrdy M, Toto R, Franco M, Szydlowski E, Verma A, Fazzio P, Tay KY, Lavoie M, Posner J, Weiss A, Delgado E.   +10 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Clinical practice patterns in the pre-endoscopic management of individuals presenting with acute upper gastrointestinal bleeding: results of an international survey. [PDF]

Ther Adv Gastroenterol
Obeidat M, Floria DE, Teutsch B, Abonyi-Tóth Z, Laursen SB, Camus M, Verdonk F, Vincze Á, Bognár Z, Drug V, Siau K, Gralnek IM, Hegyi P, Erőss B.   +13 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Developing internationally agreed core indicators for surveillance of preconception health: protocol for a consensus study. [PDF]

PLoS One
Schoenaker D, Hall J, Al-Jayyousi GF, Borges ALV, Boua PR, Chan JKY, Chitashvili T, Delbaere I, Demidova A, Fikadu K, Fisher S, Hazra A, James S, Ku CW, Maeda E, Memon Z, Munblit D, Mulders A, Murira Z, Norman WV, Ogle A, Sethi V, Shahbic HI, Kakoly NS, Verbiest S, Stephenson J, International Core Indicators for Preconception Health and Equity (iCIPHE) Alliance.   +26 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Understanding self-management and digital health needs in musicians with playing-related musculoskeletal disorders: an explanatory sequential mixed-methods study. [PDF]

BMJ Open
Eleryan N, Hemming R, Sparkes V, Sheeran L.   +3 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source